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Helmholtz Zentrum für Infektionsforschung Repository > Browsing HZI

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Showing results 1 to 20 of 26
Issue DateTitleAuthor(s)
2012 3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2.Yin, Lina; Hu, Qingzhong; Hartmann, Rolf W; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany.
Jan-2013 Activity-guided screening of bioactive natural compounds implementing a new glucocorticoid-receptor-translocation assay and detection of new anti-inflammatory steroids from bacteria.Kaufmann, Katrin; Simmons, Luke; Herrmann, Jennifer; Schwär, Gertrud; Luniak, Nora; Müller, Rolf; Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany. kaufm@uni-trier.de
28-Dec-2012 Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes.Dandekar, Prajakta; Jain, Ratnesh; Keil, Manuel; Loretz, Brigitta; Muijs, Leon; Schneider, Marc; Auerbach, Dagmar; Jung, Gregor; Lehr, Claus-Michael; Wenz, Gerhard; Department of Drug Delivery, Helmholtz-Institute for Pharmaceutical Research Saarland, Helmholtz-Center for Infection Research (HZI), Saarland University, D-66123 Saarbrücken, Germany.
Nov-2012 Characterization and evaluation of β-glucan formulations as injectable implants for protein and peptide delivery.Jacobs, Simone; Bunt, Craig R; Wu, Zimei; Lehr, Claus-Michael; Rupenthal, Ilva D; Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany.
Sep-2011 Computational investigation of the binding mode of bis(hydroxylphenyl)arenes in 17β-HSD1: molecular dynamics simulations, MM-PBSA free energy calculations, and molecular electrostatic potential maps.Negri, Matthias; Recanatini, Maurizio; Hartmann, Rolf W; Pharmaceutical and Medicinal Chemistry, Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus C2.3, 66123 Saarbrücken, Germany.
May-2012 Design, synthesis and evaluation of novel 16-imidazolyl substituted steroidal derivatives possessing potent diversified pharmacological properties.Bansal, Ranju; Guleria, Sheetal; Thota, Sridhar; Bodhankar, Subhash L; Patwardhan, Moreshwar R; Zimmer, Christina; Hartmann, Rolf W; Harvey, Alan L; University Institute of Pharmaceutical Sciences, Sector-14, Panjab University, Chandigarh 160014, India. ranju29in@yahoo.co.in
23-Mar-2012 Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa.Lu, Cenbin; Kirsch, Benjamin; Zimmer, Christina; de Jong, Johannes C; Henn, Claudia; Maurer, Christine K; Müsken, Mathias; Häussler, Susanne; Steinbach, Anke; Hartmann, Rolf W; Helmholtz Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
Aug-2012 Dissolution techniques for in vitro testing of dry powders for inhalation.May, Sabine; Jensen, Birte; Wolkenhauer, Markus; Schneider, Marc; Lehr, Claus Michael; PharmBioTec GmbH, Saarbrücken, Germany.
2013 Growth Medium-Dependent Glycine Incorporation into the Peptidoglycan of Caulobacter crescentus.Takacs, Constantin N; Hocking, Jason; Cabeen, Matthew T; Bui, Nhat Khai; Poggio, Sebastian; Vollmer, Waldemar; Jacobs-Wagner, Christine; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, United States of America.
2012 Hydroxybenzothiazoles as new nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1).Spadaro, Alessandro; Negri, Matthias; Marchais-Oberwinkler, Sandrine; Bey, Emmanuel; Frotscher, Martin; Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany.
Feb-2013 Improved input parameters for diffusion models of skin absorption.Hansen, Steffi; Lehr, Claus-Michael; Schaefer, Ulrich F; Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz-Center for Infection Research (HZI), Saarbruecken, Germany. Steffi.hansen@helmholtz-hzi.de
May-2011 Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690.Kopp, Maren; Irschik, Herbert; Gemperlein, Katja; Buntin, Kathrin; Meiser, Peter; Weissman, Kira J; Bode, Helge B; Müller, Rolf; Helmholtz Institute for Pharmaceutical Research, Helmholtz Center for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, PO Box 151150, 66041 Saarbrücken, Germany.
Apr-2011 Interaction of metal oxide nanoparticles with lung surfactant protein A.Schulze, Christine; Schaefer, Ulrich F; Ruge, Christian A; Wohlleben, Wendel; Lehr, Claus-Michael; Department of Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbruecken, Germany. chr.schulze@mx.uni-saarland.de
Feb-2013 Modeling the human skin barrier--towards a better understanding of dermal absorption.Hansen, Steffi; Lehr, Claus-Michael; Schaefer, Ulrich F
18-Sep-2010 Myxobacterial secondary metabolites: bioactivities and modes-of-action.Weissman, Kira J; Müller, Rolf; Helmholtz Institute for Pharmaceutical Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
Mar-2012 Process optimization and biocompatibility of cell carriers suitable for automated magnetic manipulation.Krejci, I; Piana, C; Howitz, S; Wegener, T; Fiedler, S; Zwanzig, M; Schmitt, D; Daum, N; Meier, K; Lehr, C M; Batista, U; Zemljic, S; Messerschmidt, J; Franzke, J; Wirth, M; Gabor, F; Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstraße 14, A-1090 Vienna, Austria.
2011 Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma.Bihrer, Verena; Waidmann, Oliver; Friedrich-Rust, Mireen; Forestier, Nicole; Susser, Simone; Haupenthal, Jörg; Welker, Martin; Shi, Ying; Peveling-Oberhag, Jan; Polta, Andreas; von Wagner, Michael; Radeke, Heinfried H; Sarrazin, Christoph; Trojan, Jörg; Zeuzem, Stefan; Kronenberger, Bernd; Piiper, Albrecht; Department of Medicine I, University of Frankfurt/M., Frankfurt, Germany.
Sep-2011 Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.Bihrer, Verena; Friedrich-Rust, Mireen; Kronenberger, Bernd; Forestier, Nicole; Haupenthal, Jörg; Shi, Ying; Peveling-Oberhag, Jan; Radeke, Heinfried H; Sarrazin, Christoph; Herrmann, Eva; Zeuzem, Stefan; Waidmann, Oliver; Piiper, Albrecht; Department of Medicine I, University of Frankfurt/M., Frankfurt, Germany.
2011 Structural basis for species specific inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1): computational study and biological validation.Klein, Tobias; Henn, Claudia; Negri, Matthias; Frotscher, Martin; Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany.
2011 Structural basis for species specific inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1): computational study and biological validation.Klein, Tobias; Henn, Claudia; Negri, Matthias; Frotscher, Martin; Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany.
Showing results 1 to 20 of 26