2.50
Hdl Handle:
http://hdl.handle.net/10033/126271
Title:
Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O.
Authors:
Gekara, Nelson O; Zietara, Natalia; Geffers, Robert; Weiss, Siegfried
Abstract:
The success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes.
Affiliation:
Molecular Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany. nelson.gekara@mims.umu.se
Citation:
Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. 2010, 202 (11):1698-707 J. Infect. Dis.
Journal:
The Journal of infectious diseases
Issue Date:
1-Dec-2010
URI:
http://hdl.handle.net/10033/126271
DOI:
10.1086/657145
PubMed ID:
20961225
Type:
Article
Language:
en
ISSN:
1537-6613
Appears in Collections:
Publications of RG Molecular Immunology (MOLI)

Full metadata record

DC FieldValue Language
dc.contributor.authorGekara, Nelson Oen
dc.contributor.authorZietara, Nataliaen
dc.contributor.authorGeffers, Roberten
dc.contributor.authorWeiss, Siegfrieden
dc.date.accessioned2011-03-30T09:08:20Z-
dc.date.available2011-03-30T09:08:20Z-
dc.date.issued2010-12-01-
dc.identifier.citationListeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. 2010, 202 (11):1698-707 J. Infect. Dis.en
dc.identifier.issn1537-6613-
dc.identifier.pmid20961225-
dc.identifier.doi10.1086/657145-
dc.identifier.urihttp://hdl.handle.net/10033/126271-
dc.description.abstractThe success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes.en
dc.language.isoenen
dc.subject.meshAnimalsen
dc.subject.meshBacterial Toxinsen
dc.subject.meshCD4-Positive T-Lymphocytesen
dc.subject.meshDisease Models, Animalen
dc.subject.meshFlow Cytometryen
dc.subject.meshGene Expressionen
dc.subject.meshHeat-Shock Proteinsen
dc.subject.meshHemolysin Proteinsen
dc.subject.meshListeria monocytogenesen
dc.subject.meshMiceen
dc.subject.meshMice, Inbred C57BLen
dc.subject.meshMicroarray Analysisen
dc.subject.meshReceptors, Antigen, T-Cellen
dc.subject.meshSpecific Pathogen-Free Organismsen
dc.titleListeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O.en
dc.typeArticleen
dc.contributor.departmentMolecular Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany. nelson.gekara@mims.umu.seen
dc.identifier.journalThe Journal of infectious diseasesen
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