| Title: | Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. |
| Authors: | Gekara, Nelson O
Zietara, Natalia
Geffers, Robert
Weiss, Siegfried |
| Affiliation: | Molecular Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany. nelson.gekara@mims.umu.se |
| Citation: | Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. 2010, 202 (11):1698-707 J. Infect. Dis. |
| Journal: | The Journal of infectious diseases |
| Issue Date: | 1-Dec-2010 |
| URI: | http://hdl.handle.net/10033/126271 |
| DOI: | 10.1086/657145 |
| PubMed ID: | 20961225 |
| Abstract: | The success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes. |
| Type: | Article |
| Language: | en |
| MeSH: | Animals
Bacterial Toxins
CD4-Positive T-Lymphocytes
Disease Models, Animal
Flow Cytometry
Gene Expression
Heat-Shock Proteins
Hemolysin Proteins
Listeria monocytogenes
Mice
Mice, Inbred C57BL
Microarray Analysis
Receptors, Antigen, T-Cell
Specific Pathogen-Free Organisms |
| ISSN: | 1537-6613 |
| Appears in Collections: | Publications of RG Molecular Immunology (MOLI)
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