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Helmholtz Zentrum für Infektionsforschung Repository > Division of Cell and Immune Biology (ZIB) > Dept. Cell Biology (ZB) > Publications of Dept. Cell Biology (ZB) > Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.


Please use this identifier to cite or link to this item: http://hdl.handle.net/10033/129760
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Title: Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.
Authors: Maahs, David M
Siwy, Justyna
Argilés, Angel
Cerna, Marie
Delles, Christian
Dominiczak, Anna F
Gayrard, Nathalie
Iphöfer, Alexander
Jänsch, Lothar
Jerums, George
Medek, Karel
Mischak, Harald
Navis, Gerjan J
Roob, Johannes M
Rossing, Kasper
Rossing, Peter
Rychlík, Ivan
Schiffer, Eric
Schmieder, Roland E
Wascher, Thomas C
Winklhofer-Roob, Brigitte M
Zimmerli, Lukas U
Zürbig, Petra
Snell-Bergeon, Janet K
Affiliation: Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, United States of America. David.Maahs@ucdenver.edu
Citation: Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. 2010, 5 (9) PLoS ONE
Journal: PloS one
Issue Date: 2010
URI: http://hdl.handle.net/10033/129760
DOI: 10.1371/journal.pone.0013051
PubMed ID: 20927192
Abstract: The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D).
Type: Article
Language: en
MeSH: Adult
Biological Markers
Cohort Studies
Collagen
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Extracellular Matrix
Female
Humans
Male
Mass Spectrometry
Middle Aged
Proteomics
ISSN: 1932-6203
Appears in Collections: Publications of Dept. Cell Biology (ZB)

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