Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.

2.50
HDL Handle:
http://hdl.handle.net/10033/129760
Title:
Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.
Authors:
Maahs, David M; Siwy, Justyna; Argilés, Angel; Cerna, Marie; Delles, Christian; Dominiczak, Anna F; Gayrard, Nathalie; Iphöfer, Alexander; Jänsch, Lothar; Jerums, George; Medek, Karel; Mischak, Harald; Navis, Gerjan J; Roob, Johannes M; Rossing, Kasper; Rossing, Peter; Rychlík, Ivan; Schiffer, Eric; Schmieder, Roland E; Wascher, Thomas C; Winklhofer-Roob, Brigitte M; Zimmerli, Lukas U; Zürbig, Petra; Snell-Bergeon, Janet K
Abstract:
The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D).
Affiliation:
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, United States of America. David.Maahs@ucdenver.edu
Citation:
Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. 2010, 5 (9) PLoS ONE
Journal:
PloS one
Issue Date:
2010
URI:
http://hdl.handle.net/10033/129760
DOI:
10.1371/journal.pone.0013051
PubMed ID:
20927192
Type:
Article
Language:
en
ISSN:
1932-6203
Appears in Collections:
Publications of Dept. Cell Biology (ZB)

Full metadata record

DC FieldValueLanguage
dc.contributor.authorMaahs, David Men
dc.contributor.authorSiwy, Justynaen
dc.contributor.authorArgilés, Angelen
dc.contributor.authorCerna, Marieen
dc.contributor.authorDelles, Christianen
dc.contributor.authorDominiczak, Anna Fen
dc.contributor.authorGayrard, Nathalieen
dc.contributor.authorIphöfer, Alexanderen
dc.contributor.authorJänsch, Lotharen
dc.contributor.authorJerums, Georgeen
dc.contributor.authorMedek, Karelen
dc.contributor.authorMischak, Haralden
dc.contributor.authorNavis, Gerjan Jen
dc.contributor.authorRoob, Johannes Men
dc.contributor.authorRossing, Kasperen
dc.contributor.authorRossing, Peteren
dc.contributor.authorRychlík, Ivanen
dc.contributor.authorSchiffer, Ericen
dc.contributor.authorSchmieder, Roland Een
dc.contributor.authorWascher, Thomas Cen
dc.contributor.authorWinklhofer-Roob, Brigitte Men
dc.contributor.authorZimmerli, Lukas Uen
dc.contributor.authorZürbig, Petraen
dc.contributor.authorSnell-Bergeon, Janet Ken
dc.date.accessioned2011-05-18T13:44:55Z-
dc.date.available2011-05-18T13:44:55Z-
dc.date.issued2010-
dc.identifier.citationUrinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. 2010, 5 (9) PLoS ONEen
dc.identifier.issn1932-6203-
dc.identifier.pmid20927192-
dc.identifier.doi10.1371/journal.pone.0013051-
dc.identifier.urihttp://hdl.handle.net/10033/129760-
dc.description.abstractThe pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D).en
dc.language.isoenen
dc.subject.meshAdulten
dc.subject.meshBiological Markersen
dc.subject.meshCohort Studiesen
dc.subject.meshCollagenen
dc.subject.meshDiabetes Mellitus, Type 1en
dc.subject.meshDiabetes Mellitus, Type 2en
dc.subject.meshExtracellular Matrixen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMass Spectrometryen
dc.subject.meshMiddle Ageden
dc.subject.meshProteomicsen
dc.titleUrinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.en
dc.typeArticleen
dc.contributor.departmentBarbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, United States of America. David.Maahs@ucdenver.eduen
dc.identifier.journalPloS oneen

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