2.50
Hdl Handle:
http://hdl.handle.net/10033/14602
Title:
The making of filopodia.
Authors:
Faix, Jan; Rottner, Klemens
Abstract:
Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been ascribed sensory or exploratory functions. Filopodium formation is frequently associated with protrusion of sheet-like actin filament arrays called lamellipodia and membrane ruffles, but, in comparison to these structures, the molecular details underpinning the initiation and maintenance of filopodia are only just beginning to emerge. Recent advances have improved our understanding of the molecular requirements for filopodium protrusion and have yielded insights into the inter-relationships between lamellipodia and filopodia, the two 'sub-compartments' of the protrusive actin cytoskeleton.
Citation:
Curr. Opin. Cell Biol. 2006, 18(1):18-25
Issue Date:
1-Feb-2006
URI:
http://hdl.handle.net/10033/14602
DOI:
10.1016/j.ceb.2005.11.002
PubMed ID:
16337369
Type:
Article
Language:
en
ISSN:
0955-0674
Appears in Collections:
Publications of RG Cytoskeleton Dynamics (CYD)

Full metadata record

DC FieldValue Language
dc.contributor.authorFaix, Jan-
dc.contributor.authorRottner, Klemens-
dc.date.accessioned2007-11-16T15:25:43Z-
dc.date.available2007-11-16T15:25:43Z-
dc.date.issued2006-02-01-
dc.identifier.citationCurr. Opin. Cell Biol. 2006, 18(1):18-25en
dc.identifier.issn0955-0674-
dc.identifier.pmid16337369-
dc.identifier.doi10.1016/j.ceb.2005.11.002-
dc.identifier.urihttp://hdl.handle.net/10033/14602-
dc.description.abstractFilopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been ascribed sensory or exploratory functions. Filopodium formation is frequently associated with protrusion of sheet-like actin filament arrays called lamellipodia and membrane ruffles, but, in comparison to these structures, the molecular details underpinning the initiation and maintenance of filopodia are only just beginning to emerge. Recent advances have improved our understanding of the molecular requirements for filopodium protrusion and have yielded insights into the inter-relationships between lamellipodia and filopodia, the two 'sub-compartments' of the protrusive actin cytoskeleton.en
dc.format.extent487397 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.titleThe making of filopodia.en
dc.typeArticleen
dc.format.digYES-

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