The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo. - Helmholtz Zentrum für Infektionsforschung Repository

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Helmholtz Zentrum für Infektionsforschung Repository > Dept. Epidemiologie (EPID) > Publications of the department of epidemiology (EPID) > The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.

Please use this identifier to cite or link to this item: http://hdl.handle.net/10033/214592
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Title:	The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.
Authors:	Kukita, Akiko Kukita, Toshio Nagata, Kengo Teramachi, Junpei Li, Yin-Ji Yoshida, Hiroki Miyamoto, Hiroshi Gay, Steffen Pessler, Frank Shobuike, Takeo
Affiliation:	Department of Microbiology, Faculty of Medicine, Saga University, Saga, Japan. kukita@cc.saga-u.ac.jp
Citation:	The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo. 2011, 63 (9):2744-54 Arthritis Rheum.
Journal:	Arthritis and rheumatism
Issue Date:	Sep-2011
URI:	http://hdl.handle.net/10033/214592
DOI:	10.1002/art.30455
PubMed ID:	21590684
Abstract:	Since transcription factors expressed in osteoclasts are possible targets for regulation of bone destruction in bone disorders, we investigated the expression of the transcription factor FBI-1/OCZF/LRF (in humans, factor that binds to inducer of short transcripts of human immunodeficiency virus type 1; in rats, osteoclast-derived zinc finger; in mice, leukemia/lymphoma-related factor) in patients with rheumatoid arthritis (RA), and assessed its role in osteoclastogenesis in vivo.
Type:	Article
Language:	en
MeSH:	Animals Arthritis, Experimental Arthritis, Rheumatoid Bone Density Bone and Bones Cell Differentiation DNA-Binding Proteins Female Humans Macrophages Male Mice Mice, Transgenic Osteoblasts Osteoclasts RANK Ligand Rats Transcription Factors
ISSN:	1529-0131
Appears in Collections:	Publications of the department of epidemiology (EPID)

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