2.50
Hdl Handle:
http://hdl.handle.net/10033/216864
Title:
Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.
Authors:
TrehanPati, Nirupma; Sukriti, Sukriti; Geffers, Robert; Hissar, Syed; Riese, Peggy ( 0000-0001-6796-6780 ) ; Toepfer, Tanja; Guzman, Carlos A; Sarin, Shiv Kumar
Abstract:
Approximately 50% of acute viral hepatitis in young adults and in pregnant women is due to hepatitis E virus (HEV) infection in developing countries. T cell-mediated immune injury probably plays a key role in the pathogenesis of acute hepatitis illness. However, there is a paucity of data on the global gene expression programs activated on T cells, which are subsequently responsible for T cell recruitment to the liver and triggering of immune injury.
Affiliation:
Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, 110 070, New Delhi, India. trehanpati@gmail.com
Citation:
Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. 2011, 31 (3):498-508 J. Clin. Immunol.
Journal:
Journal of clinical immunology
Issue Date:
Jun-2011
URI:
http://hdl.handle.net/10033/216864
DOI:
10.1007/s10875-010-9506-2
PubMed ID:
21287396
Type:
Article
Language:
en
ISSN:
1573-2592
Appears in Collections:
publications of the research group vaccinology and applied microbiology (VAC)

Full metadata record

DC FieldValue Language
dc.contributor.authorTrehanPati, Nirupmaen_GB
dc.contributor.authorSukriti, Sukritien_GB
dc.contributor.authorGeffers, Roberten_GB
dc.contributor.authorHissar, Syeden_GB
dc.contributor.authorRiese, Peggyen_GB
dc.contributor.authorToepfer, Tanjaen_GB
dc.contributor.authorGuzman, Carlos Aen_GB
dc.contributor.authorSarin, Shiv Kumaren_GB
dc.date.accessioned2012-03-28T13:19:57Zen
dc.date.available2012-03-28T13:19:57Zen
dc.date.issued2011-06en
dc.identifier.citationGene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. 2011, 31 (3):498-508 J. Clin. Immunol.en_GB
dc.identifier.issn1573-2592en
dc.identifier.pmid21287396en
dc.identifier.doi10.1007/s10875-010-9506-2en
dc.identifier.urihttp://hdl.handle.net/10033/216864en
dc.description.abstractApproximately 50% of acute viral hepatitis in young adults and in pregnant women is due to hepatitis E virus (HEV) infection in developing countries. T cell-mediated immune injury probably plays a key role in the pathogenesis of acute hepatitis illness. However, there is a paucity of data on the global gene expression programs activated on T cells, which are subsequently responsible for T cell recruitment to the liver and triggering of immune injury.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Journal of clinical immunologyen_GB
dc.subject.meshAcute Diseaseen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAntigens, CD11aen_GB
dc.subject.meshAntigens, CD45en_GB
dc.subject.meshBiological Markersen_GB
dc.subject.meshCase-Control Studiesen_GB
dc.subject.meshConvalescenceen_GB
dc.subject.meshDisease Progressionen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFlow Cytometryen_GB
dc.subject.meshGene Expression Profilingen_GB
dc.subject.meshHepatitis Een_GB
dc.subject.meshHepatitis E virusen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLiveren_GB
dc.subject.meshMaleen_GB
dc.subject.meshOligonucleotide Array Sequence Analysisen_GB
dc.subject.meshReceptors, CCR5en_GB
dc.subject.meshReverse Transcriptase Polymerase Chain Reactionen_GB
dc.subject.meshT-Lymphocytesen_GB
dc.subject.meshYoung Adulten_GB
dc.titleGene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.en
dc.typeArticleen
dc.contributor.departmentInstitute of Liver and Biliary Sciences, D-1, Vasant Kunj, 110 070, New Delhi, India. trehanpati@gmail.comen_GB
dc.identifier.journalJournal of clinical immunologyen_GB

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