2.50
HDL Handle:
http://hdl.handle.net/10033/22353
Title:
MUGEN mouse database; animal models of human immunological diseases.
Authors:
Aidinis, V; Chandras, C; Manoloukos, M; Thanassopoulou, A; Kranidioti, K; Armaka, M; Douni, E; Kontoyiannis, D L; Zouberakis, M; Kollias, G
Abstract:
The MUGEN mouse database (MMdb) (www.mugen-noe.org/database/) is a database of murine models of immune processes and immunological diseases. Its aim is to share and publicize information on mouse strain characteristics and availability from participating institutions. MMdb's basic classification of models is based on three major research application categories: Models of Human Disease, Models of Immune Processes and Transgenic Tools. Data on mutant strains includes detailed information on affected gene(s), mutant allele(s) and genetic background (DNA origin, gene targeted, host and backcross strain background). Each gene/transgene index also includes IDs and direct links to Ensembl, ArrayExpress, EURExpress and NCBI's Entrez Gene database. Phenotypic description is standardized and hierarchically structured, based on MGI's mammalian phenotypic ontology terms. Availability (e.g. live mice, cryopreserved embryos, sperm and ES cells) is clearly indicated, along with handling and genotyping details (in the form of documents or hyperlinks) and all relevant contact information (including EMMA and Jax/IMSR hyperlinks where available). MMdb's design offers a user-friendly query interface and provides instant access to the list of mutant strains and genes. Database access is free of charge and there are no registration requirements for data querying.
Affiliation:
B.S.R.C. Alexander Fleming, 34 Fleming Street, 16672, Vari, Greece. v.aidinis@fleming.gr
Citation:
MUGEN mouse database; animal models of human immunological diseases. 2008, 36 (Database issue):D1048-54 Nucleic Acids Res.
Journal:
Nucleic acids research
Issue Date:
Jan-2008
URI:
http://hdl.handle.net/10033/22353
DOI:
10.1093/nar/gkm838
PubMed ID:
17932065
Additional Links:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17932065
Type:
Article
Language:
en
ISSN:
1362-4962
Appears in Collections:
Publications of Dept. Experimental Immunology (EI)

Full metadata record

DC FieldValueLanguage
dc.contributor.authorAidinis, V-
dc.contributor.authorChandras, C-
dc.contributor.authorManoloukos, M-
dc.contributor.authorThanassopoulou, A-
dc.contributor.authorKranidioti, K-
dc.contributor.authorArmaka, M-
dc.contributor.authorDouni, E-
dc.contributor.authorKontoyiannis, D L-
dc.contributor.authorZouberakis, M-
dc.contributor.authorKollias, G-
dc.date.accessioned2008-04-04T14:39:02Z-
dc.date.available2008-04-04T14:39:02Z-
dc.date.issued2008-01-
dc.identifier.citationMUGEN mouse database; animal models of human immunological diseases. 2008, 36 (Database issue):D1048-54 Nucleic Acids Res.en
dc.identifier.issn1362-4962-
dc.identifier.pmid17932065-
dc.identifier.doi10.1093/nar/gkm838-
dc.identifier.urihttp://hdl.handle.net/10033/22353-
dc.description.abstractThe MUGEN mouse database (MMdb) (www.mugen-noe.org/database/) is a database of murine models of immune processes and immunological diseases. Its aim is to share and publicize information on mouse strain characteristics and availability from participating institutions. MMdb's basic classification of models is based on three major research application categories: Models of Human Disease, Models of Immune Processes and Transgenic Tools. Data on mutant strains includes detailed information on affected gene(s), mutant allele(s) and genetic background (DNA origin, gene targeted, host and backcross strain background). Each gene/transgene index also includes IDs and direct links to Ensembl, ArrayExpress, EURExpress and NCBI's Entrez Gene database. Phenotypic description is standardized and hierarchically structured, based on MGI's mammalian phenotypic ontology terms. Availability (e.g. live mice, cryopreserved embryos, sperm and ES cells) is clearly indicated, along with handling and genotyping details (in the form of documents or hyperlinks) and all relevant contact information (including EMMA and Jax/IMSR hyperlinks where available). MMdb's design offers a user-friendly query interface and provides instant access to the list of mutant strains and genes. Database access is free of charge and there are no registration requirements for data querying.en
dc.language.isoenen
dc.relation.urlhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17932065en
dc.subject.meshAnimalsen
dc.subject.meshDatabases, Geneticen
dc.subject.meshDisease Models, Animalen
dc.subject.meshImmune System Diseasesen
dc.subject.meshImmunityen
dc.subject.meshInterneten
dc.subject.meshMiceen
dc.subject.meshMice, Mutant Strainsen
dc.subject.meshMice, Transgenicen
dc.subject.meshPhenotypeen
dc.subject.meshUser-Computer Interfaceen
dc.titleMUGEN mouse database; animal models of human immunological diseases.en
dc.typeArticleen
dc.contributor.departmentB.S.R.C. Alexander Fleming, 34 Fleming Street, 16672, Vari, Greece. v.aidinis@fleming.gren
dc.identifier.journalNucleic acids researchen

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