Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.

2.50
HDL Handle:
http://hdl.handle.net/10033/237053
Title:
Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.
Authors:
Fava, E; Dehghany, J; Ouwendijk, J; Müller, A; Niederlein, A; Verkade, P; Meyer-Hermann, M; Solimena, M
Abstract:
Knowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size.
Affiliation:
Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.
Citation:
Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling. 2012, 55 (4):1013-23 Diabetologia
Journal:
Diabetologia
Issue Date:
Apr-2012
URI:
http://hdl.handle.net/10033/237053
DOI:
10.1007/s00125-011-2438-4
PubMed ID:
22252472
Type:
Article
Language:
en
ISSN:
1432-0428
Appears in Collections:
publications of the division system immunology (SIMM)

Full metadata record

DC FieldValueLanguage
dc.contributor.authorFava, Een_GB
dc.contributor.authorDehghany, Jen_GB
dc.contributor.authorOuwendijk, Jen_GB
dc.contributor.authorMüller, Aen_GB
dc.contributor.authorNiederlein, Aen_GB
dc.contributor.authorVerkade, Pen_GB
dc.contributor.authorMeyer-Hermann, Men_GB
dc.contributor.authorSolimena, Men_GB
dc.date.accessioned2012-08-02T13:06:00Z-
dc.date.available2012-08-02T13:06:00Z-
dc.date.issued2012-04-
dc.identifier.citationNovel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling. 2012, 55 (4):1013-23 Diabetologiaen_GB
dc.identifier.issn1432-0428-
dc.identifier.pmid22252472-
dc.identifier.doi10.1007/s00125-011-2438-4-
dc.identifier.urihttp://hdl.handle.net/10033/237053-
dc.description.abstractKnowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Diabetologiaen_GB
dc.titleNovel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.en
dc.typeArticleen
dc.contributor.departmentMax Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.en_GB
dc.identifier.journalDiabetologiaen_GB

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