Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.
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Issue Date
2012-04
Metadata
Show full item recordAbstract
Knowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size.Citation
Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling. 2012, 55 (4):1013-23 DiabetologiaAffiliation
Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.Journal
DiabetologiaPubMed ID
22252472Type
ArticleLanguage
enISSN
1432-0428ae974a485f413a2113503eed53cd6c53
10.1007/s00125-011-2438-4
Scopus Count
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