Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien.
Name:
Publisher version
View Source
Access full-text PDFOpen Access
View Source
Check access options
Check access options
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
2012-09-01
Metadata
Show full item recordAbstract
Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium.Citation
Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien. 2012, 22 (17):5731-4 Bioorg. Med. Chem. Lett.Affiliation
Organische Chemie, Ruprecht-Karls-Universität Heidelberg, INF 270, D-69120 Heidelberg, Germany.PubMed ID
22832317Type
ArticleLanguage
enISSN
1464-3405ae974a485f413a2113503eed53cd6c53
10.1016/j.bmcl.2012.06.070
Scopus Count
The following license files are associated with this item:
Related articles
- Design, synthesis and biological evaluation of simplified analogues of the RNA polymerase inhibitor etnangien.
- Authors: Menche D, Li P, Irschik H
- Issue date: 2010 Feb 1
- Modular synthesis of polyene side chain analogues of the potent macrolide antibiotic etnangien by a flexible coupling strategy based on hetero-bis-metallated alkenes.
- Authors: Altendorfer M, Raja A, Sasse F, Irschik H, Menche D
- Issue date: 2013 Apr 7
- Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases.
- Authors: Irschik H, Schummer D, Höfle G, Reichenbach H, Steinmetz H, Jansen R
- Issue date: 2007 Jun
- A new series of macrolide derivatives with 4''-O-saccharide substituents.
- Authors: Xu P, Chen XZ, Liu L, Jin ZP, Lei PS
- Issue date: 2010 Sep 15
- Total synthesis of etnangien.
- Authors: Li P, Li J, Arikan F, Ahlbrecht W, Dieckmann M, Menche D
- Issue date: 2009 Aug 26