| Title: | Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien. |
| Authors: | Altendorfer, Mario Irschik, Herbert Menche, Dirk |
| Affiliation: | Organische Chemie, Ruprecht-Karls-Universität Heidelberg, INF 270, D-69120 Heidelberg, Germany. |
| Citation: | Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien. 2012, 22 (17):5731-4 Bioorg. Med. Chem. Lett. |
| Journal: | Bioorganic & medicinal chemistry letters |
| Issue Date: | 1-Sep-2012 |
| URI: | http://hdl.handle.net/10033/245811 |
| DOI: | 10.1016/j.bmcl.2012.06.070 |
| PubMed ID: | 22832317 |
| Abstract: | Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium. |
| Type: | Article |
| Language: | en |
| ISSN: | 1464-3405 |
| Appears in Collections: | Publications of RG Microbial Drugs (MWIS)
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| Files in This Item: |
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| Altendorfer et al_final.pdf | final submission | 1210Kb | Adobe PDF |  View/Open |
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