2.50
Hdl Handle:
http://hdl.handle.net/10033/297472
Title:
Host-pathogen interactions in streptococcal immune sequelae.
Authors:
Nitsche-Schmitz, D Patric; Chhatwal, Gursharan S
Abstract:
Otherwise uncomplicated infections with Streptococcus pyogenes can cause two insidious immune sequelae known as post-streptococcal glomerulonephritis (PSGN) and acute rheumatic fever (ARF). These diseases follow with a latency of a few weeks or months after primary infection and are responsible for high mortality and morbidity. PSGN has also been linked to infections with group C streptococci of the species S. equi ssp. zooepidemicus (SESZ). Moreover, there are some indications that infection with group C and G streptococci (GCGS) of the subspecies Streptococcus dysgalactiae ssp. equisimilis (SDSE) leads to ARF. Despite decades of research, the picture of the molecular pathogenesis of streptococcal immune sequelae resembles a jigsaw puzzle. Herein we try to put some of the puzzle bits together that have been collected till date.
Affiliation:
Helmholtz Centre for Infection Research, Inhoffenstraße 7, D-38124 Braunschweig, Germany. Patric.Nitsche@helmholtz-hzi.de
Citation:
Host-pathogen interactions in streptococcal immune sequelae. 2013, 368:155-71 Curr. Top. Microbiol. Immunol.
Journal:
Current topics in microbiology and immunology
Issue Date:
2013
URI:
http://hdl.handle.net/10033/297472
DOI:
10.1007/82_2012_296
PubMed ID:
23212184
Type:
Book chapter
Language:
en
ISSN:
0070-217X
Appears in Collections:
Publications of Dept. Medizinische Mikrobiologie (MMIK)

Full metadata record

DC FieldValue Language
dc.contributor.authorNitsche-Schmitz, D Patricen_GB
dc.contributor.authorChhatwal, Gursharan Sen_GB
dc.date.accessioned2013-08-07T08:58:11Z-
dc.date.available2013-08-07T08:58:11Z-
dc.date.issued2013-
dc.identifier.citationHost-pathogen interactions in streptococcal immune sequelae. 2013, 368:155-71 Curr. Top. Microbiol. Immunol.en_GB
dc.identifier.issn0070-217X-
dc.identifier.pmid23212184-
dc.identifier.doi10.1007/82_2012_296-
dc.identifier.urihttp://hdl.handle.net/10033/297472-
dc.description.abstractOtherwise uncomplicated infections with Streptococcus pyogenes can cause two insidious immune sequelae known as post-streptococcal glomerulonephritis (PSGN) and acute rheumatic fever (ARF). These diseases follow with a latency of a few weeks or months after primary infection and are responsible for high mortality and morbidity. PSGN has also been linked to infections with group C streptococci of the species S. equi ssp. zooepidemicus (SESZ). Moreover, there are some indications that infection with group C and G streptococci (GCGS) of the subspecies Streptococcus dysgalactiae ssp. equisimilis (SDSE) leads to ARF. Despite decades of research, the picture of the molecular pathogenesis of streptococcal immune sequelae resembles a jigsaw puzzle. Herein we try to put some of the puzzle bits together that have been collected till date.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Current topics in microbiology and immunologyen_GB
dc.subject.meshAnimalsen_GB
dc.subject.meshAntigens, Bacterialen_GB
dc.subject.meshBacterial Outer Membrane Proteinsen_GB
dc.subject.meshCarrier Proteinsen_GB
dc.subject.meshGlomerulonephritisen_GB
dc.subject.meshHost-Pathogen Interactionsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshRheumatic Feveren_GB
dc.subject.meshRheumatic Heart Diseaseen_GB
dc.subject.meshStreptococcal Infectionsen_GB
dc.subject.meshStreptococcusen_GB
dc.titleHost-pathogen interactions in streptococcal immune sequelae.en
dc.typeBook chapteren
dc.contributor.departmentHelmholtz Centre for Infection Research, Inhoffenstraße 7, D-38124 Braunschweig, Germany. Patric.Nitsche@helmholtz-hzi.deen_GB
dc.identifier.journalCurrent topics in microbiology and immunologyen_GB

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