The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification.

2.50
Hdl Handle:
http://hdl.handle.net/10033/300668
Title:
The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification.
Authors:
Della Beffa, Cristina; Slansky, Elisabeth; Pommerenke, Claudia ( 0000-0002-9448-416X ) ; Klawonn, Frank; Li, Jialiang; Dai, Lie; Schumacher, H Ralph; Pessler, Frank
Abstract:
Traditionally, differences in absolute numbers of cells expressing a certain marker (e.g., positive staining cells per mm(2)) have been used in immunohistological synovial tissue classification. We have begun to evaluate the relative composition of the inflammatory infiltrates, i.e. percentages of inflammatory cell types in inflammatory infiltrates, as an alternate classification tool that may potentially improve tissue diagnostics, subgrouping in clinical trials, and understanding of pathogenesis of inflammatory and noninflammatory arthropathies.
Affiliation:
Department of Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Citation:
The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification. 2013, 8 (8):e72494 PLoS ONE
Journal:
PloS one
Issue Date:
2013
URI:
http://hdl.handle.net/10033/300668
DOI:
10.1371/journal.pone.0072494
PubMed ID:
23951325
Type:
Article
Language:
en
ISSN:
1932-6203
Appears in Collections:
publications of the research group cellular proteom research (CPRO)

Full metadata record

DC FieldValue Language
dc.contributor.authorDella Beffa, Cristinaen_GB
dc.contributor.authorSlansky, Elisabethen_GB
dc.contributor.authorPommerenke, Claudiaen_GB
dc.contributor.authorKlawonn, Franken_GB
dc.contributor.authorLi, Jialiangen_GB
dc.contributor.authorDai, Lieen_GB
dc.contributor.authorSchumacher, H Ralphen_GB
dc.contributor.authorPessler, Franken_GB
dc.date.accessioned2013-09-03T10:33:55Zen
dc.date.available2013-09-03T10:33:55Zen
dc.date.issued2013en
dc.identifier.citationThe relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification. 2013, 8 (8):e72494 PLoS ONEen_GB
dc.identifier.issn1932-6203en
dc.identifier.pmid23951325en
dc.identifier.doi10.1371/journal.pone.0072494en
dc.identifier.urihttp://hdl.handle.net/10033/300668en
dc.description.abstractTraditionally, differences in absolute numbers of cells expressing a certain marker (e.g., positive staining cells per mm(2)) have been used in immunohistological synovial tissue classification. We have begun to evaluate the relative composition of the inflammatory infiltrates, i.e. percentages of inflammatory cell types in inflammatory infiltrates, as an alternate classification tool that may potentially improve tissue diagnostics, subgrouping in clinical trials, and understanding of pathogenesis of inflammatory and noninflammatory arthropathies.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to PloS oneen_GB
dc.titleThe relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification.en
dc.typeArticleen
dc.contributor.departmentDepartment of Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany.en_GB
dc.identifier.journalPloS oneen_GB

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