Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers.

2.50
Hdl Handle:
http://hdl.handle.net/10033/303738
Title:
Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers.
Authors:
Köberle, Verena; Pleli, Thomas; Schmithals, Christian; Augusto Alonso, Eduardo; Haupenthal, Jörg; Bönig, Halvard; Peveling-Oberhag, Jan; Biondi, Ricardo M; Zeuzem, Stefan; Kronenberger, Bernd; Waidmann, Oliver; Piiper, Albrecht
Abstract:
MicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipids/vesicles for their stability and use as biomarkers are largely unexplored and are subject of the present study.
Affiliation:
Department of Medicine I, University Hospital Frankfurt, Frankfurt, Germany.
Citation:
Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers. 2013, 8 (9):e75184 PLoS ONE
Journal:
PloS one
Issue Date:
2013
URI:
http://hdl.handle.net/10033/303738
DOI:
10.1371/journal.pone.0075184
PubMed ID:
24073250
Type:
Article
Language:
en
ISSN:
1932-6203
Appears in Collections:
publications of the department drug design and optimization (HIPS]DDOP)

Full metadata record

DC FieldValue Language
dc.contributor.authorKöberle, Verenaen
dc.contributor.authorPleli, Thomasen
dc.contributor.authorSchmithals, Christianen
dc.contributor.authorAugusto Alonso, Eduardoen
dc.contributor.authorHaupenthal, Jörgen
dc.contributor.authorBönig, Halvarden
dc.contributor.authorPeveling-Oberhag, Janen
dc.contributor.authorBiondi, Ricardo Men
dc.contributor.authorZeuzem, Stefanen
dc.contributor.authorKronenberger, Bernden
dc.contributor.authorWaidmann, Oliveren
dc.contributor.authorPiiper, Albrechten
dc.date.accessioned2013-10-21T14:39:02Z-
dc.date.available2013-10-21T14:39:02Z-
dc.date.issued2013-
dc.identifier.citationDifferential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers. 2013, 8 (9):e75184 PLoS ONEen
dc.identifier.issn1932-6203-
dc.identifier.pmid24073250-
dc.identifier.doi10.1371/journal.pone.0075184-
dc.identifier.urihttp://hdl.handle.net/10033/303738-
dc.description.abstractMicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipids/vesicles for their stability and use as biomarkers are largely unexplored and are subject of the present study.en
dc.language.isoenen
dc.rightsArchived with thanks to PloS oneen
dc.titleDifferential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medicine I, University Hospital Frankfurt, Frankfurt, Germany.en
dc.identifier.journalPloS oneen

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