2.00
Hdl Handle:
http://hdl.handle.net/10033/304838
Title:
Therapeutic strategies for tendon healing based on novel biomaterials, factors and cells.
Authors:
Gross, Gerhard; Hoffmann, Andrea
Abstract:
The repair of tendon injuries still presents a major clinical challenge to orthopedic medicine. Tendons, like some other tissues, are poorly vascularized and heal slowly. In addition, healing often leads to the formation of fibrous tissue and scar tissue which lack flexibility and biomechanical properties. So the treatment of tendon injuries is challenging. We give an overview of the structure and composition of tendons, pathological states of tendon and natural healing, as well as therapeutic options. We focus in particular on biomaterials that have been specifically developed or suggested for the successful repair of tendon injuries. In addition, we also review factor- and cell-dependent strategies to heal tendon and ligament disorders. Although brief, we hope that this review will be helpful, particularly for those readers who are new to the field of tendon tissue engineering.
Affiliation:
Department of Molecular Biotechnology, Signalling and Gene Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Citation:
Therapeutic strategies for tendon healing based on novel biomaterials, factors and cells. 2013, 80 (4):203-10 Pathobiology
Journal:
Pathobiology : journal of immunopathology, molecular and cellular biology
Issue Date:
2013
URI:
http://hdl.handle.net/10033/304838
DOI:
10.1159/000347059
PubMed ID:
23652284
Type:
Article
Language:
en
ISSN:
1423-0291
Appears in Collections:
Publications of Dept. Gene Regulation and Differentiation (RDIF)

Full metadata record

DC FieldValue Language
dc.contributor.authorGross, Gerharden
dc.contributor.authorHoffmann, Andreaen
dc.date.accessioned2013-10-31T10:36:45Z-
dc.date.available2013-10-31T10:36:45Z-
dc.date.issued2013-
dc.identifier.citationTherapeutic strategies for tendon healing based on novel biomaterials, factors and cells. 2013, 80 (4):203-10 Pathobiologyen
dc.identifier.issn1423-0291-
dc.identifier.pmid23652284-
dc.identifier.doi10.1159/000347059-
dc.identifier.urihttp://hdl.handle.net/10033/304838-
dc.description.abstractThe repair of tendon injuries still presents a major clinical challenge to orthopedic medicine. Tendons, like some other tissues, are poorly vascularized and heal slowly. In addition, healing often leads to the formation of fibrous tissue and scar tissue which lack flexibility and biomechanical properties. So the treatment of tendon injuries is challenging. We give an overview of the structure and composition of tendons, pathological states of tendon and natural healing, as well as therapeutic options. We focus in particular on biomaterials that have been specifically developed or suggested for the successful repair of tendon injuries. In addition, we also review factor- and cell-dependent strategies to heal tendon and ligament disorders. Although brief, we hope that this review will be helpful, particularly for those readers who are new to the field of tendon tissue engineering.en
dc.language.isoenen
dc.rightsArchived with thanks to Pathobiology : journal of immunopathology, molecular and cellular biologyen
dc.titleTherapeutic strategies for tendon healing based on novel biomaterials, factors and cells.en
dc.typeArticleen
dc.contributor.departmentDepartment of Molecular Biotechnology, Signalling and Gene Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany.en
dc.identifier.journalPathobiology : journal of immunopathology, molecular and cellular biologyen

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