2.50
Hdl Handle:
http://hdl.handle.net/10033/336700
Title:
New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.
Authors:
Sommer, Roman; Joachim, Ines; Wagner, Stefanie; Titz, Alexander
Abstract:
Hospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.
Affiliation:
University of Konstanz, Department of Chemistry and Zukunftskolleg, Universitätsstrasse 10, D-78457 Konstanz.
Citation:
New approaches to control infections: anti-biofilm strategies against gram-negative bacteria. 2013, 67 (4):286-90 Chimia (Aarau)
Journal:
Chimia
Issue Date:
2013
URI:
http://hdl.handle.net/10033/336700
PubMed ID:
23967708
Type:
Article
Language:
en
ISSN:
0009-4293
Appears in Collections:
publications of the junior research group chemical biology of carbohydrates ([HIPS]CBCH)

Full metadata record

DC FieldValue Language
dc.contributor.authorSommer, Romanen
dc.contributor.authorJoachim, Inesen
dc.contributor.authorWagner, Stefanieen
dc.contributor.authorTitz, Alexanderen
dc.date.accessioned2014-12-05T09:59:07Z-
dc.date.available2014-12-05T09:59:07Z-
dc.date.issued2013-
dc.identifier.citationNew approaches to control infections: anti-biofilm strategies against gram-negative bacteria. 2013, 67 (4):286-90 Chimia (Aarau)en
dc.identifier.issn0009-4293-
dc.identifier.pmid23967708-
dc.identifier.urihttp://hdl.handle.net/10033/336700-
dc.description.abstractHospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.en
dc.language.isoenen
dc.subject.meshAnti-Bacterial Agentsen
dc.subject.meshBiofilmsen
dc.subject.meshCross Infectionen
dc.subject.meshGram-Negative Bacteriaen
dc.subject.meshGram-Negative Bacterial Infectionsen
dc.subject.meshHumansen
dc.titleNew approaches to control infections: anti-biofilm strategies against gram-negative bacteria.en
dc.typeArticleen
dc.contributor.departmentUniversity of Konstanz, Department of Chemistry and Zukunftskolleg, Universitätsstrasse 10, D-78457 Konstanz.en
dc.identifier.journalChimiaen
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