The CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae.

2.50
Hdl Handle:
http://hdl.handle.net/10033/338679
Title:
The CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae.
Authors:
Wang, Hui; Ziesche, Lisa; Frank, Oliver; Michael, Victoria; Martin, Madeleine; Petersen, Jörn; Schulz, Stefan; Wagner-Döbler, Irene; Tomasch, Jürgen
Abstract:
Dinoroseobacter shibae, a member of the Roseobacter clade abundant in marine environments, maintains morphological heterogeneity throughout growth, with small cells dividing by binary fission and large cells dividing by budding from one or both cell poles. This morphological heterogeneity is lost if the quorum sensing (QS) system is silenced, concurrent with a decreased expression of the CtrA phosphorelay, a regulatory system conserved in Alphaproteobacteria and the master regulator of the Caulobacter crescentus cell cycle. It consists of the sensor histidine kinase CckA, the phosphotransferase ChpT and the transcriptional regulator CtrA. Here we tested if the QS induced differentiation of D. shibae is mediated by the CtrA phosphorelay.
Affiliation:
Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Citation:
The CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae. 2014, 15:130 BMC Genomics
Journal:
BMC genomics
Issue Date:
2014
URI:
http://hdl.handle.net/10033/338679
DOI:
10.1186/1471-2164-15-130
PubMed ID:
24524855
Type:
Article
Language:
en
ISSN:
1471-2164
Appears in Collections:
collections of the research group microbial communication (KOM)

Full metadata record

DC FieldValue Language
dc.contributor.authorWang, Huien
dc.contributor.authorZiesche, Lisaen
dc.contributor.authorFrank, Oliveren
dc.contributor.authorMichael, Victoriaen
dc.contributor.authorMartin, Madeleineen
dc.contributor.authorPetersen, Jörnen
dc.contributor.authorSchulz, Stefanen
dc.contributor.authorWagner-Döbler, Ireneen
dc.contributor.authorTomasch, Jürgenen
dc.date.accessioned2015-01-22T16:26:11Z-
dc.date.available2015-01-22T16:26:11Z-
dc.date.issued2014-
dc.identifier.citationThe CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae. 2014, 15:130 BMC Genomicsen
dc.identifier.issn1471-2164-
dc.identifier.pmid24524855-
dc.identifier.doi10.1186/1471-2164-15-130-
dc.identifier.urihttp://hdl.handle.net/10033/338679-
dc.description.abstractDinoroseobacter shibae, a member of the Roseobacter clade abundant in marine environments, maintains morphological heterogeneity throughout growth, with small cells dividing by binary fission and large cells dividing by budding from one or both cell poles. This morphological heterogeneity is lost if the quorum sensing (QS) system is silenced, concurrent with a decreased expression of the CtrA phosphorelay, a regulatory system conserved in Alphaproteobacteria and the master regulator of the Caulobacter crescentus cell cycle. It consists of the sensor histidine kinase CckA, the phosphotransferase ChpT and the transcriptional regulator CtrA. Here we tested if the QS induced differentiation of D. shibae is mediated by the CtrA phosphorelay.en
dc.language.isoenen
dc.subject.meshAcyl-Butyrolactonesen
dc.subject.meshBacterial Proteinsen
dc.subject.meshBinding Sitesen
dc.subject.meshEvolution, Molecularen
dc.subject.meshMultigene Familyen
dc.subject.meshPhenotypeen
dc.subject.meshPromoter Regions, Geneticen
dc.subject.meshQuorum Sensingen
dc.subject.meshRhodobacteraceaeen
dc.subject.meshTranscription Factorsen
dc.subject.meshTranscriptomeen
dc.titleThe CtrA phosphorelay integrates differentiation and communication in the marine alphaproteobacterium Dinoroseobacter shibae.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.en
dc.identifier.journalBMC genomicsen

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