Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56.

2.50
Hdl Handle:
http://hdl.handle.net/10033/345407
Title:
Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56.
Authors:
Khatri, Yogan; Hannemann, Frank; Perlova, Olena; Müller, Rolf; Bernhardt, Rita
Abstract:
The exploitation of cytochromes P450 for novel biotechnological application and for the investigation of their physiological function is of great scientific interest in this post genomic era, where an extraordinary biodiversity of P450 genes has been derived from all forms of life. The study of P450s in the myxobacterium Sorangium cellulosum strain So ce56, the producer of novel secondary metabolites of pharmaceutical interest is the research topic, in which we were engaged since the beginning of its genome sequencing project. We herein disclosed the cytochrome P450 complements (CYPomes) of spore-forming myxobacterial species, Stigmatella aurantiaca DW4/3-1, Haliangium ochraceum DSM 14365 and Myxococcus xanthus DK1622, and their potential pharmaceutical significance has been discussed.
Citation:
Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56. 2011, 585 (11):1506-13 FEBS Lett.
Journal:
FEBS letters
Issue Date:
6-Jun-2011
URI:
http://hdl.handle.net/10033/345407
DOI:
10.1016/j.febslet.2011.04.035
PubMed ID:
21521637
Type:
Article
Language:
en
ISSN:
1873-3468
Appears in Collections:
publications of the department of microbial natural substances ([HIPS]MINS)

Full metadata record

DC FieldValue Language
dc.contributor.authorKhatri, Yoganen
dc.contributor.authorHannemann, Franken
dc.contributor.authorPerlova, Olenaen
dc.contributor.authorMüller, Rolfen
dc.contributor.authorBernhardt, Ritaen
dc.date.accessioned2015-02-26T12:43:15Zen
dc.date.available2015-02-26T12:43:15Zen
dc.date.issued2011-06-06en
dc.identifier.citationInvestigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56. 2011, 585 (11):1506-13 FEBS Lett.en
dc.identifier.issn1873-3468en
dc.identifier.pmid21521637en
dc.identifier.doi10.1016/j.febslet.2011.04.035en
dc.identifier.urihttp://hdl.handle.net/10033/345407en
dc.description.abstractThe exploitation of cytochromes P450 for novel biotechnological application and for the investigation of their physiological function is of great scientific interest in this post genomic era, where an extraordinary biodiversity of P450 genes has been derived from all forms of life. The study of P450s in the myxobacterium Sorangium cellulosum strain So ce56, the producer of novel secondary metabolites of pharmaceutical interest is the research topic, in which we were engaged since the beginning of its genome sequencing project. We herein disclosed the cytochrome P450 complements (CYPomes) of spore-forming myxobacterial species, Stigmatella aurantiaca DW4/3-1, Haliangium ochraceum DSM 14365 and Myxococcus xanthus DK1622, and their potential pharmaceutical significance has been discussed.en
dc.language.isoenen
dc.subject.meshCytochrome P-450 Enzyme Systemen
dc.subject.meshGenome, Bacterialen
dc.subject.meshGenomicsen
dc.subject.meshMyxococcalesen
dc.subject.meshSpores, Bacterialen
dc.titleInvestigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56.en
dc.typeArticleen
dc.identifier.journalFEBS lettersen

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