Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources.

2.50
Hdl Handle:
http://hdl.handle.net/10033/48394
Title:
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources.
Authors:
Hancock, John M; Adams, Niels C; Aidinis, Vassilis; Blake, Andrew; Bogue, Molly; Brown, Steve D M; Chesler, Elissa J; Davidson, Duncan; Duran, Christopher; Eppig, Janan T; Gailus-Durner, Valérie; Gates, Hilary; Gkoutos, Georgios V; Greenaway, Simon; Hrabé de Angelis, Martin; Kollias, George; Leblanc, Sophie; Lee, Kirsty; Lengger, Christoph; Maier, Holger; Mallon, Ann-Marie; Masuya, Hiroshi; Melvin, David G; Müller, Werner; Parkinson, Helen; Proctor, Glenn; Reuveni, Eli; Schofield, Paul; Shukla, Aadya; Smith, Cynthia; Toyoda, Tetsuro; Vasseur, Laurent; Wakana, Shigeharu; Walling, Alison; White, Jacqui; Wood, Joe; Zouberakis, Michalis
Abstract:
Understanding the functions encoded in the mouse genome will be central to an understanding of the genetic basis of human disease. To achieve this it will be essential to be able to characterize the phenotypic consequences of variation and alterations in individual genes. Data on the phenotypes of mouse strains are currently held in a number of different forms (detailed descriptions of mouse lines, first-line phenotyping data on novel mutations, data on the normal features of inbred lines) at many sites worldwide. For the most efficient use of these data sets, we have initiated a process to develop standards for the description of phenotypes (using ontologies) and file formats for the description of phenotyping protocols and phenotype data sets. This process is ongoing and needs to be supported by the wider mouse genetics and phenotyping communities to succeed. We invite interested parties to contact us as we develop this process further.
Citation:
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. 2007, 18 (3):157-63 Mamm. Genome
Journal:
Mammalian genome : official journal of the International Mammalian Genome Society
Issue Date:
Mar-2007
URI:
http://hdl.handle.net/10033/48394
DOI:
10.1007/s00335-007-9004-x
PubMed ID:
17436037
Type:
Article
Language:
en
ISSN:
0938-8990
Appears in Collections:
Publications of Dept. Experimental Immunology (EI)

Full metadata record

DC FieldValue Language
dc.contributor.authorHancock, John M-
dc.contributor.authorAdams, Niels C-
dc.contributor.authorAidinis, Vassilis-
dc.contributor.authorBlake, Andrew-
dc.contributor.authorBogue, Molly-
dc.contributor.authorBrown, Steve D M-
dc.contributor.authorChesler, Elissa J-
dc.contributor.authorDavidson, Duncan-
dc.contributor.authorDuran, Christopher-
dc.contributor.authorEppig, Janan T-
dc.contributor.authorGailus-Durner, Valérie-
dc.contributor.authorGates, Hilary-
dc.contributor.authorGkoutos, Georgios V-
dc.contributor.authorGreenaway, Simon-
dc.contributor.authorHrabé de Angelis, Martin-
dc.contributor.authorKollias, George-
dc.contributor.authorLeblanc, Sophie-
dc.contributor.authorLee, Kirsty-
dc.contributor.authorLengger, Christoph-
dc.contributor.authorMaier, Holger-
dc.contributor.authorMallon, Ann-Marie-
dc.contributor.authorMasuya, Hiroshi-
dc.contributor.authorMelvin, David G-
dc.contributor.authorMüller, Werner-
dc.contributor.authorParkinson, Helen-
dc.contributor.authorProctor, Glenn-
dc.contributor.authorReuveni, Eli-
dc.contributor.authorSchofield, Paul-
dc.contributor.authorShukla, Aadya-
dc.contributor.authorSmith, Cynthia-
dc.contributor.authorToyoda, Tetsuro-
dc.contributor.authorVasseur, Laurent-
dc.contributor.authorWakana, Shigeharu-
dc.contributor.authorWalling, Alison-
dc.contributor.authorWhite, Jacqui-
dc.contributor.authorWood, Joe-
dc.contributor.authorZouberakis, Michalis-
dc.date.accessioned2009-02-03T15:13:12Z-
dc.date.available2009-02-03T15:13:12Z-
dc.date.issued2007-03-
dc.identifier.citationMouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. 2007, 18 (3):157-63 Mamm. Genomeen
dc.identifier.issn0938-8990-
dc.identifier.pmid17436037-
dc.identifier.doi10.1007/s00335-007-9004-x-
dc.identifier.urihttp://hdl.handle.net/10033/48394-
dc.description.abstractUnderstanding the functions encoded in the mouse genome will be central to an understanding of the genetic basis of human disease. To achieve this it will be essential to be able to characterize the phenotypic consequences of variation and alterations in individual genes. Data on the phenotypes of mouse strains are currently held in a number of different forms (detailed descriptions of mouse lines, first-line phenotyping data on novel mutations, data on the normal features of inbred lines) at many sites worldwide. For the most efficient use of these data sets, we have initiated a process to develop standards for the description of phenotypes (using ontologies) and file formats for the description of phenotyping protocols and phenotype data sets. This process is ongoing and needs to be supported by the wider mouse genetics and phenotyping communities to succeed. We invite interested parties to contact us as we develop this process further.en
dc.language.isoenen
dc.subject.meshAnimalsen
dc.subject.meshDatabases, Geneticen
dc.subject.meshGenomicsen
dc.subject.meshMiceen
dc.subject.meshMice, Inbred Strainsen
dc.subject.meshMice, Mutant Strainsen
dc.subject.meshPhenotypeen
dc.titleMouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources.en
dc.typeArticleen
dc.identifier.journalMammalian genome : official journal of the International Mammalian Genome Societyen

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