The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility.

2.50
Hdl Handle:
http://hdl.handle.net/10033/528570
Title:
The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility.
Authors:
Menhofer, Magdalena H; Kubisch, Rebekka; Schreiner, Laura; Zorn, Matthias; Foerster, Florian; Mueller, Rolf; Raedler, Joachim O; Wagner, Ernst; Vollmar, Angelika M; Zahler, Stefan
Abstract:
A major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent.
Affiliation:
Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbru ¨ cken, Germany.
Citation:
The actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility. 2014, 9 (11):e112542 PLoS ONE
Journal:
PloS one
Issue Date:
2014
URI:
http://hdl.handle.net/10033/528570
DOI:
10.1371/journal.pone.0112542
PubMed ID:
25391145
Type:
Article
Language:
en
ISSN:
1932-6203
Appears in Collections:
publications of the department of microbial natural substances ([HIPS]MINS)

Full metadata record

DC FieldValue Language
dc.contributor.authorMenhofer, Magdalena Hen
dc.contributor.authorKubisch, Rebekkaen
dc.contributor.authorSchreiner, Lauraen
dc.contributor.authorZorn, Matthiasen
dc.contributor.authorFoerster, Florianen
dc.contributor.authorMueller, Rolfen
dc.contributor.authorRaedler, Joachim Oen
dc.contributor.authorWagner, Ernsten
dc.contributor.authorVollmar, Angelika Men
dc.contributor.authorZahler, Stefanen
dc.date.accessioned2015-04-13T12:56:41Zen
dc.date.available2015-04-13T12:56:41Zen
dc.date.issued2014en
dc.identifier.citationThe actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility. 2014, 9 (11):e112542 PLoS ONEen
dc.identifier.issn1932-6203en
dc.identifier.pmid25391145en
dc.identifier.doi10.1371/journal.pone.0112542en
dc.identifier.urihttp://hdl.handle.net/10033/528570en
dc.description.abstractA major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent.en
dc.language.isoenen
dc.titleThe actin targeting compound Chondramide inhibits breast cancer metastasis via reduction of cellular contractility.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbru ¨ cken, Germany.en
dc.identifier.journalPloS oneen

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