2.50
Hdl Handle:
http://hdl.handle.net/10033/578559
Title:
CMV and Immunosenescence: from basics to clinics.
Authors:
Solana, Rafael; Tarazona, Raquel; Aiello, Allison E; Akbar, Arne N; Appay, Victor; Beswick, Mark; Bosch, Jos A; Campos, Carmen; Cantisán, Sara; Cicin-Sain, Luka ( 0000-0003-3978-778X ) ; Derhovanessian, Evelyna; Ferrando-Martínez, Sara; Frasca, Daniela; Fulöp, Tamas; Govind, Sheila; Grubeck-Loebenstein, Beatrix; Hill, Ann; Hurme, Mikko; Kern, Florian; Larbi, Anis; López-Botet, Miguel; Maier, Andrea B; McElhaney, Janet E; Moss, Paul; Naumova, Elissaveta; Nikolich-Zugich, Janko; Pera, Alejandra; Rector, Jerrald L; Riddell, Natalie; Sanchez-Correa, Beatriz; Sansoni, Paolo; Sauce, Delphine; van Lier, Rene; Wang, George C; Wills, Mark R; Zieliński, Maciej; Pawelec, Graham
Abstract:
Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates "immunosenescence". This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.
Affiliation:
Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Citation:
CMV and Immunosenescence: from basics to clinics. 2012, 9 (1):23 Immun Ageing
Journal:
Immunity & ageing : I & A
Issue Date:
2012
URI:
http://hdl.handle.net/10033/578559
DOI:
10.1186/1742-4933-9-23
PubMed ID:
23114110
Type:
Article
Language:
en
ISSN:
1742-4933
Appears in Collections:
publications of the research group immune aging and chronic infections (IMCI)

Full metadata record

DC FieldValue Language
dc.contributor.authorSolana, Rafaelen
dc.contributor.authorTarazona, Raquelen
dc.contributor.authorAiello, Allison Een
dc.contributor.authorAkbar, Arne Nen
dc.contributor.authorAppay, Victoren
dc.contributor.authorBeswick, Marken
dc.contributor.authorBosch, Jos Aen
dc.contributor.authorCampos, Carmenen
dc.contributor.authorCantisán, Saraen
dc.contributor.authorCicin-Sain, Lukaen
dc.contributor.authorDerhovanessian, Evelynaen
dc.contributor.authorFerrando-Martínez, Saraen
dc.contributor.authorFrasca, Danielaen
dc.contributor.authorFulöp, Tamasen
dc.contributor.authorGovind, Sheilaen
dc.contributor.authorGrubeck-Loebenstein, Beatrixen
dc.contributor.authorHill, Annen
dc.contributor.authorHurme, Mikkoen
dc.contributor.authorKern, Florianen
dc.contributor.authorLarbi, Anisen
dc.contributor.authorLópez-Botet, Miguelen
dc.contributor.authorMaier, Andrea Ben
dc.contributor.authorMcElhaney, Janet Een
dc.contributor.authorMoss, Paulen
dc.contributor.authorNaumova, Elissavetaen
dc.contributor.authorNikolich-Zugich, Jankoen
dc.contributor.authorPera, Alejandraen
dc.contributor.authorRector, Jerrald Len
dc.contributor.authorRiddell, Natalieen
dc.contributor.authorSanchez-Correa, Beatrizen
dc.contributor.authorSansoni, Paoloen
dc.contributor.authorSauce, Delphineen
dc.contributor.authorvan Lier, Reneen
dc.contributor.authorWang, George Cen
dc.contributor.authorWills, Mark Ren
dc.contributor.authorZieliński, Maciejen
dc.contributor.authorPawelec, Grahamen
dc.date.accessioned2015-09-21T14:03:35Zen
dc.date.available2015-09-21T14:03:35Zen
dc.date.issued2012en
dc.identifier.citationCMV and Immunosenescence: from basics to clinics. 2012, 9 (1):23 Immun Ageingen
dc.identifier.issn1742-4933en
dc.identifier.pmid23114110en
dc.identifier.doi10.1186/1742-4933-9-23en
dc.identifier.urihttp://hdl.handle.net/10033/578559en
dc.description.abstractAlone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates "immunosenescence". This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.en
dc.language.isoenen
dc.titleCMV and Immunosenescence: from basics to clinics.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.en
dc.identifier.journalImmunity & ageing : I & Aen

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