Focused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles.

5.00
Hdl Handle:
http://hdl.handle.net/10033/578673
Title:
Focused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles.
Authors:
Schiller, Stefan; Hanefeld, Andrea; Schneider, Marc ( 0000-0002-9260-7357 ) ; Lehr, Claus-Michael
Abstract:
Although nanomaterials are under investigation for a very broad range of medical applications, only a small fraction of these are already commercialized or in clinical development. A major challenge for the translation of nanomedicines into the clinic is the missing scalability of the available lab scale preparation methods and, ultimately, non-identical samples during early and late research.
Affiliation:
Helmholtz Institute for Pharmaceutical Research Saarland,Saarbru¨ cken, Saarland 66123, Germany.
Citation:
Focused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles. 2015, 32 (9):2995-3006 Pharm. Res.
Journal:
Pharmaceutical research
Issue Date:
Sep-2015
URI:
http://hdl.handle.net/10033/578673
DOI:
10.1007/s11095-015-1681-7
PubMed ID:
25823648
Type:
Article
Language:
en
ISSN:
1573-904X
Appears in Collections:
publications of the department drug delivery ([TC] DDEL)

Full metadata record

DC FieldValue Language
dc.contributor.authorSchiller, Stefanen
dc.contributor.authorHanefeld, Andreaen
dc.contributor.authorSchneider, Marcen
dc.contributor.authorLehr, Claus-Michaelen
dc.date.accessioned2015-09-24T08:32:31Zen
dc.date.available2015-09-24T08:32:31Zen
dc.date.issued2015-09en
dc.identifier.citationFocused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles. 2015, 32 (9):2995-3006 Pharm. Res.en
dc.identifier.issn1573-904Xen
dc.identifier.pmid25823648en
dc.identifier.doi10.1007/s11095-015-1681-7en
dc.identifier.urihttp://hdl.handle.net/10033/578673en
dc.description.abstractAlthough nanomaterials are under investigation for a very broad range of medical applications, only a small fraction of these are already commercialized or in clinical development. A major challenge for the translation of nanomedicines into the clinic is the missing scalability of the available lab scale preparation methods and, ultimately, non-identical samples during early and late research.en
dc.language.isoenen
dc.titleFocused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Institute for Pharmaceutical Research Saarland,Saarbru¨ cken, Saarland 66123, Germany.en
dc.identifier.journalPharmaceutical researchen

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