Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells.

2.50
Hdl Handle:
http://hdl.handle.net/10033/593753
Title:
Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells.
Authors:
Lindenberg, Marc; Solmaz, Gulhas; Puttur, Franz; Sparwasser, Tim ( 0000-0001-5645-902X )
Abstract:
Cytomegalovirus establishes lifelong persistency in the host and leads to life threatening situations in immunocompromised patients. FoxP3+ T regulatory cells (Tregs) critically control and suppress innate and adaptive immune responses. However, their specific role during MCMV infection, especially pertaining to their interaction with NK cells, remains incompletely defined.
Affiliation:
TWINCORE, Centre for Experimental and Clinical Infection Research GmbH, Feodor-Lynen-Str. 3-7, 30625 Hannover, Germany.
Citation:
Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells. 2014, 11:145 Virol. J.
Journal:
Virology journal
Issue Date:
2014
URI:
http://hdl.handle.net/10033/593753
DOI:
10.1186/1743-422X-11-145
PubMed ID:
25108672
Type:
Article
Language:
en
ISSN:
1743-422X
Appears in Collections:
publications of the TwinCore unit Infection immunology

Full metadata record

DC FieldValue Language
dc.contributor.authorLindenberg, Marcen
dc.contributor.authorSolmaz, Gulhasen
dc.contributor.authorPuttur, Franzen
dc.contributor.authorSparwasser, Timen
dc.date.accessioned2016-01-18T15:42:57Zen
dc.date.available2016-01-18T15:42:57Zen
dc.date.issued2014en
dc.identifier.citationMouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells. 2014, 11:145 Virol. J.en
dc.identifier.issn1743-422Xen
dc.identifier.pmid25108672en
dc.identifier.doi10.1186/1743-422X-11-145en
dc.identifier.urihttp://hdl.handle.net/10033/593753en
dc.description.abstractCytomegalovirus establishes lifelong persistency in the host and leads to life threatening situations in immunocompromised patients. FoxP3+ T regulatory cells (Tregs) critically control and suppress innate and adaptive immune responses. However, their specific role during MCMV infection, especially pertaining to their interaction with NK cells, remains incompletely defined.en
dc.language.isoenen
dc.subject.meshAdaptive Immunityen
dc.subject.meshAnimalsen
dc.subject.meshForkhead Transcription Factorsen
dc.subject.meshHerpesviridae Infectionsen
dc.subject.meshHomeostasisen
dc.subject.meshInterferon-gammaen
dc.subject.meshKiller Cells, Naturalen
dc.subject.meshLymphocyte Activationen
dc.subject.meshLymphocyte Counten
dc.subject.meshLymphocyte Depletionen
dc.subject.meshMaleen
dc.subject.meshMiceen
dc.subject.meshMuromegalovirusen
dc.subject.meshPhenotypeen
dc.subject.meshT-Lymphocyte Subsetsen
dc.subject.meshT-Lymphocytes, Regulatoryen
dc.subject.meshViral Loaden
dc.titleMouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells.en
dc.typeArticleen
dc.contributor.departmentTWINCORE, Centre for Experimental and Clinical Infection Research GmbH, Feodor-Lynen-Str. 3-7, 30625 Hannover, Germany.en
dc.identifier.journalVirology journalen

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