2.50
Hdl Handle:
http://hdl.handle.net/10033/90154
Title:
Innovative strategies for treatment of soft tissue injuries in human and animal athletes.
Authors:
Hoffmann, Andrea; Gross, Gerhard
Abstract:
Our aim is to review the recent progress in the management of musculoskeletal disorders. We will cover novel therapeutic approaches based on growth factors, gene therapy and cells, including stem cells, which may be combined with each other as appropriate. We focus mainly on the treatment of soft tissue injuries - muscle, cartilage, and tendon/ligament for both human and animal athletes. The need for innovative strategies results from the fact that despite all efforts, the current strategies for cartilage and tendon/ligament still result in the formation of functionally and biomechanically inferior tissues after injury (a phenomenon called 'repair' as opposed to proper 'regeneration'), whereas the outcome for muscle is more favorable. Innovative approaches are urgently needed not only to enhance the outcome of conservative or surgical procedures but also to speed up the healing process from the very long disabling periods, which is of special relevance for athletes.
Affiliation:
Department of Molecular Biotechnology, Helmholtz Centre for Infection Research, Braunschweig, Germany. Andrea.Hoffmann@helmholtz-hzi.de
Citation:
Innovative strategies for treatment of soft tissue injuries in human and animal athletes. 2009, 54:150-65 Med Sport Sci
Journal:
Medicine and sport science
Issue Date:
2009
URI:
http://hdl.handle.net/10033/90154
DOI:
10.1159/000235702
PubMed ID:
19696513
Type:
Article
Language:
en
ISSN:
0254-5020
Appears in Collections:
Publications of Dept. Gene Regulation and Differentiation (RDIF)

Full metadata record

DC FieldValue Language
dc.contributor.authorHoffmann, Andreaen
dc.contributor.authorGross, Gerharden
dc.date.accessioned2010-01-20T15:25:54Z-
dc.date.available2010-01-20T15:25:54Z-
dc.date.issued2009-
dc.identifier.citationInnovative strategies for treatment of soft tissue injuries in human and animal athletes. 2009, 54:150-65 Med Sport Scien
dc.identifier.issn0254-5020-
dc.identifier.pmid19696513-
dc.identifier.doi10.1159/000235702-
dc.identifier.urihttp://hdl.handle.net/10033/90154-
dc.description.abstractOur aim is to review the recent progress in the management of musculoskeletal disorders. We will cover novel therapeutic approaches based on growth factors, gene therapy and cells, including stem cells, which may be combined with each other as appropriate. We focus mainly on the treatment of soft tissue injuries - muscle, cartilage, and tendon/ligament for both human and animal athletes. The need for innovative strategies results from the fact that despite all efforts, the current strategies for cartilage and tendon/ligament still result in the formation of functionally and biomechanically inferior tissues after injury (a phenomenon called 'repair' as opposed to proper 'regeneration'), whereas the outcome for muscle is more favorable. Innovative approaches are urgently needed not only to enhance the outcome of conservative or surgical procedures but also to speed up the healing process from the very long disabling periods, which is of special relevance for athletes.en
dc.language.isoenen
dc.subject.meshAnimalsen
dc.subject.meshAthletic Injuriesen
dc.subject.meshBone Morphogenetic Proteinsen
dc.subject.meshCartilageen
dc.subject.meshExercise Therapyen
dc.subject.meshGene Therapyen
dc.subject.meshGene Transfer Techniquesen
dc.subject.meshHumansen
dc.subject.meshLigamentsen
dc.subject.meshMesenchymal Stem Cell Transplantationen
dc.subject.meshMuscle, Skeletalen
dc.subject.meshPhysical Conditioning, Animalen
dc.subject.meshRegenerationen
dc.subject.meshSoft Tissue Injuriesen
dc.subject.meshTendon Injuriesen
dc.subject.meshTendonsen
dc.subject.meshWound Healingen
dc.titleInnovative strategies for treatment of soft tissue injuries in human and animal athletes.en
dc.typeArticleen
dc.contributor.departmentDepartment of Molecular Biotechnology, Helmholtz Centre for Infection Research, Braunschweig, Germany. Andrea.Hoffmann@helmholtz-hzi.deen
dc.identifier.journalMedicine and sport scienceen

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