Immune responses induced in cattle by vaccination with a recombinant adenovirus expressing Mycobacterial antigen 85A and Mycobacterium bovis BCG.
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Issue Date
2006-02-01
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Show full item recordAbstract
Cattle were vaccinated with an adenovirus expressing the mycobacterial antigen 85A (rAd85A), with Mycobacterium bovis BCG followed by rAd85A heterologous boosting, or with rAd85A followed by BCG boosting. BCG/rAd85A resulted in the highest direct gamma interferon responses. Cultured enzyme-linked immunospot assay analysis demonstrated that memory responses were induced by all three protocols but were strongest after BCG/rAd85A and rAd85A/BCG vaccination.Citation
Infect. Immun. 2006, 74(2):1416-8PubMed ID
16428796Type
ArticleLanguage
enISSN
0019-9567ae974a485f413a2113503eed53cd6c53
10.1128/IAI.74.2.1416-1418.2006
Scopus Count
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