New insights into the molecular pathology of radiation-induced pneumopathy.

Cappuccini, Federica; Eldh, Therese; Bruder, Dunja; Gereke, Marcus; Jastrow, Holger; Schulze-Osthoff, Klaus; Fischer, Ute; Köhler, David; Stuschke, Martin; Jendrossek, Verena

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Authors

Cappuccini, Federica
Eldh, Therese
Bruder, Dunja

Gereke, Marcus
Jastrow, Holger
Schulze-Osthoff, Klaus
Fischer, Ute
Köhler, David
Stuschke, Martin
Jendrossek, Verena

Issue Date

2011-10

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Abstract

Pneumonitis and fibrosis constitute dose-limiting side effects of thorax or total body irradiation. An improved understanding of the underlying mechanisms is a prerequisite for the development of effective radioprotective strategies. Here we characterized the behavior of resident and immune cells in a murine model of radiation-induced pneumopathy.

Citation

New insights into the molecular pathology of radiation-induced pneumopathy. 2011, 101 (1):86-92 Radiother Oncol

Affiliation

Institute of Cell Biology (Cancer Research), University Hospital Essen, Germany.

PubMed ID

21722981

Type

Article

Language

ISSN

1879-0887

Collections

publications of the work group immunoregulation ([HZI] IREG)

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