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dc.contributor.authorFofana, Isabel
dc.contributor.authorFafi-Kremer, Samira
dc.contributor.authorCarolla, Patric
dc.contributor.authorFauvelle, Catherine
dc.contributor.authorZahid, Muhammad Nauman
dc.contributor.authorTurek, Marine
dc.contributor.authorHeydmann, Laura
dc.contributor.authorCury, Karine
dc.contributor.authorHayer, Juliette
dc.contributor.authorCombet, Christophe
dc.contributor.authorCosset, François-Loïc
dc.contributor.authorPietschmann, Thomas
dc.contributor.authorHiet, Marie-Sophie
dc.contributor.authorBartenschlager, Ralf
dc.contributor.authorHabersetzer, François
dc.contributor.authorDoffoël, Michel
dc.contributor.authorKeck, Zhen-Yong
dc.contributor.authorFoung, Steven K H
dc.contributor.authorZeisel, Mirjam B
dc.contributor.authorStoll-Keller, Françoise
dc.contributor.authorBaumert, Thomas F
dc.date.accessioned2013-02-25T10:38:41Z
dc.date.available2013-02-25T10:38:41Z
dc.date.issued2012-07
dc.identifier.citationMutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies. 2012, 143 (1):223-233.e9 Gastroenterologyen_GB
dc.identifier.issn1528-0012
dc.identifier.pmid22503792
dc.identifier.doi10.1053/j.gastro.2012.04.006
dc.identifier.urihttp://hdl.handle.net/10033/270312
dc.description.abstractThe development of vaccines and other strategies to prevent hepatitis C virus (HCV) infection is limited by rapid viral evasion. HCV entry is the first step of infection; this process involves several viral and host factors and is targeted by host-neutralizing responses. Although the roles of host factors in HCV entry have been well characterized, their involvement in evasion of immune responses is poorly understood. We used acute infection of liver graft as a model to investigate the molecular mechanisms of viral evasion.
dc.language.isoenen
dc.rightsArchived with thanks to Gastroenterologyen_GB
dc.subject.meshAntibodies, Neutralizingen_GB
dc.subject.meshCell Line, Tumoren_GB
dc.subject.meshHepacivirusen_GB
dc.subject.meshHepatitis Cen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMutationen_GB
dc.subject.meshTransplantsen_GB
dc.subject.meshVirus Internalizationen_GB
dc.titleMutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies.en
dc.typeArticleen
dc.contributor.departmentInserm, U748, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.en_GB
dc.identifier.journalGastroenterologyen_GB
refterms.dateFOA2018-06-13T14:13:07Z
html.description.abstractThe development of vaccines and other strategies to prevent hepatitis C virus (HCV) infection is limited by rapid viral evasion. HCV entry is the first step of infection; this process involves several viral and host factors and is targeted by host-neutralizing responses. Although the roles of host factors in HCV entry have been well characterized, their involvement in evasion of immune responses is poorly understood. We used acute infection of liver graft as a model to investigate the molecular mechanisms of viral evasion.


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