Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis.
dc.contributor.author | Rohde, Manfred | |
dc.contributor.author | Chhatwal, G Singh | |
dc.date.accessioned | 2013-08-07T09:02:06Z | |
dc.date.available | 2013-08-07T09:02:06Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. 2013, 368:83-110 Curr. Top. Microbiol. Immunol. | en_GB |
dc.identifier.issn | 0070-217X | |
dc.identifier.pmid | 23203001 | |
dc.identifier.doi | 10.1007/82_2012_281 | |
dc.identifier.uri | http://hdl.handle.net/10033/297473 | |
dc.description.abstract | Streptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to Current topics in microbiology and immunology | en_GB |
dc.subject.mesh | Adhesins, Bacterial | en_GB |
dc.subject.mesh | Bacterial Adhesion | en_GB |
dc.subject.mesh | Epithelial Cells | en_GB |
dc.subject.mesh | Humans | en_GB |
dc.subject.mesh | Streptococcal Infections | en_GB |
dc.subject.mesh | Streptococcus | en_GB |
dc.title | Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. | en |
dc.type | Book chapter | en |
dc.contributor.department | Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany. manfred.rohde@helmholtz-hzi.de | en_GB |
dc.identifier.journal | Current topics in microbiology and immunology | en_GB |
refterms.dateFOA | 2013-12-15T00:00:00Z | |
html.description.abstract | Streptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections. |
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