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dc.contributor.authorRohde, Manfred
dc.contributor.authorChhatwal, G Singh
dc.date.accessioned2013-08-07T09:02:06Z
dc.date.available2013-08-07T09:02:06Z
dc.date.issued2013
dc.identifier.citationAdherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. 2013, 368:83-110 Curr. Top. Microbiol. Immunol.en_GB
dc.identifier.issn0070-217X
dc.identifier.pmid23203001
dc.identifier.doi10.1007/82_2012_281
dc.identifier.urihttp://hdl.handle.net/10033/297473
dc.description.abstractStreptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections.
dc.language.isoenen
dc.rightsArchived with thanks to Current topics in microbiology and immunologyen_GB
dc.subject.meshAdhesins, Bacterialen_GB
dc.subject.meshBacterial Adhesionen_GB
dc.subject.meshEpithelial Cellsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshStreptococcal Infectionsen_GB
dc.subject.meshStreptococcusen_GB
dc.titleAdherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis.en
dc.typeBook chapteren
dc.contributor.departmentDepartment of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany. manfred.rohde@helmholtz-hzi.deen_GB
dc.identifier.journalCurrent topics in microbiology and immunologyen_GB
refterms.dateFOA2013-12-15T00:00:00Z
html.description.abstractStreptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections.


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