Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.
dc.contributor.author | Kanjarawi, Reem | |
dc.contributor.author | Dy, Michel | |
dc.contributor.author | Bardel, Emilie | |
dc.contributor.author | Sparwasser, Tim | |
dc.contributor.author | Dubois, Bertrand | |
dc.contributor.author | Mecheri, Salah | |
dc.contributor.author | Kaiserlian, Dominique | |
dc.date.accessioned | 2013-11-11T15:14:32Z | en |
dc.date.available | 2013-11-11T15:14:32Z | en |
dc.date.issued | 2013 | en |
dc.identifier.citation | Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis. 2013, 8 (7):e69183 PLoS ONE | en |
dc.identifier.issn | 1932-6203 | en |
dc.identifier.pmid | 23922690 | en |
dc.identifier.doi | 10.1371/journal.pone.0069183 | en |
dc.identifier.uri | http://hdl.handle.net/10033/305199 | en |
dc.description.abstract | Anaphylaxis is a life-threatening outcome of immediate-type hypersensitivity to allergen, consecutive to mast cell degranulation by allergen-specific IgE. Regulatory T cells (Treg) can control allergic sensitization and mast cell degranulation, yet their clinical benefit on anaphylactic symptoms is poorly documented. Here we investigated whether Treg action during the effector arm of the allergic response alleviates anaphylaxis. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to PloS one | en |
dc.title | Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis. | en |
dc.type | Article | en |
dc.contributor.department | CIRI, International Center for Infectiology Research, Mucosal immunity, Vaccination & Biotherapies Team, Université de Lyon, Lyon, France. | en |
dc.identifier.journal | PloS one | en |
refterms.dateFOA | 2018-06-12T22:01:35Z | |
html.description.abstract | Anaphylaxis is a life-threatening outcome of immediate-type hypersensitivity to allergen, consecutive to mast cell degranulation by allergen-specific IgE. Regulatory T cells (Treg) can control allergic sensitization and mast cell degranulation, yet their clinical benefit on anaphylactic symptoms is poorly documented. Here we investigated whether Treg action during the effector arm of the allergic response alleviates anaphylaxis. |
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publications of the TwinCore unit Infection immunology [80]
Publications of the Twincore Experimentelle Infektionsforschung