Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies.
dc.contributor.author | Steinbach, Anke | |
dc.contributor.author | Maurer, Christine K | |
dc.contributor.author | Weidel, Elisabeth | |
dc.contributor.author | Henn, Claudia | |
dc.contributor.author | Brengel, Christian | |
dc.contributor.author | Hartmann, Rolf W | |
dc.contributor.author | Negri, Matthias | |
dc.date.accessioned | 2014-01-16T14:53:04Z | en |
dc.date.available | 2014-01-16T14:53:04Z | en |
dc.date.issued | 2013 | en |
dc.identifier.citation | Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies. 2013, 6 (1):10 BMC Biophys | en |
dc.identifier.issn | 2046-1682 | en |
dc.identifier.pmid | 23916145 | en |
dc.identifier.doi | 10.1186/2046-1682-6-10 | en |
dc.identifier.uri | http://hdl.handle.net/10033/311421 | en |
dc.description.abstract | PQS (PseudomonasQuinolone Signal) and its precursor HHQ are signal molecules of the P. aeruginosa quorum sensing system. They explicate their role in mammalian pathogenicity by binding to the receptor PqsR that induces virulence factor production and biofilm formation. The enzyme PqsD catalyses the biosynthesis of HHQ. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to BMC biophysics | en |
dc.title | Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies. | en |
dc.type | Article | en |
dc.identifier.journal | BMC biophysics | en |
refterms.dateFOA | 2018-06-12T23:48:53Z | |
html.description.abstract | PQS (PseudomonasQuinolone Signal) and its precursor HHQ are signal molecules of the P. aeruginosa quorum sensing system. They explicate their role in mammalian pathogenicity by binding to the receptor PqsR that induces virulence factor production and biofilm formation. The enzyme PqsD catalyses the biosynthesis of HHQ. |