Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?
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Issue Date
2014
Metadata
Show full item recordAbstract
In order to identify new scaffolds for drug discovery, surface plasmon resonance is frequently used to screen structurally diverse libraries. Usually, hit rates are low and identification processes are time consuming. Hence, approaches which improve hit rates and, thus, reduce the library size are required.Citation
Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity? 2014, 6 (18):2057-72 Future Med ChemJournal
Future medicinal chemistryPubMed ID
25531968Type
ArticleLanguage
enISSN
1756-8927ae974a485f413a2113503eed53cd6c53
10.4155/fmc.14.142
Scopus Count
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