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dc.contributor.authorWang, Mingxun
dc.contributor.authorCarver, Jeremy J
dc.contributor.authorPhelan, Vanessa V
dc.contributor.authorSanchez, Laura M
dc.contributor.authorGarg, Neha
dc.contributor.authorPeng, Yao
dc.contributor.authorNguyen, Don Duy
dc.contributor.authorWatrous, Jeramie
dc.contributor.authorKapono, Clifford A
dc.contributor.authorLuzzatto-Knaan, Tal
dc.contributor.authorPorto, Carla
dc.contributor.authorBouslimani, Amina
dc.contributor.authorMelnik, Alexey V
dc.contributor.authorMeehan, Michael J
dc.contributor.authorLiu, Wei-Ting
dc.contributor.authorCrüsemann, Max
dc.contributor.authorBoudreau, Paul D
dc.contributor.authorEsquenazi, Eduardo
dc.contributor.authorSandoval-Calderón, Mario
dc.contributor.authorKersten, Roland D
dc.contributor.authorPace, Laura A
dc.contributor.authorQuinn, Robert A
dc.contributor.authorDuncan, Katherine R
dc.contributor.authorHsu, Cheng-Chih
dc.contributor.authorFloros, Dimitrios J
dc.contributor.authorGavilan, Ronnie G
dc.contributor.authorKleigrewe, Karin
dc.contributor.authorNorthen, Trent
dc.contributor.authorDutton, Rachel J
dc.contributor.authorParrot, Delphine
dc.contributor.authorCarlson, Erin E
dc.contributor.authorAigle, Bertrand
dc.contributor.authorMichelsen, Charlotte F
dc.contributor.authorJelsbak, Lars
dc.contributor.authorSohlenkamp, Christian
dc.contributor.authorPevzner, Pavel
dc.contributor.authorEdlund, Anna
dc.contributor.authorMcLean, Jeffrey
dc.contributor.authorPiel, Jörn
dc.contributor.authorMurphy, Brian T
dc.contributor.authorGerwick, Lena
dc.contributor.authorLiaw, Chih-Chuang
dc.contributor.authorYang, Yu-Liang
dc.contributor.authorHumpf, Hans-Ulrich
dc.contributor.authorMaansson, Maria
dc.contributor.authorKeyzers, Robert A
dc.contributor.authorSims, Amy C
dc.contributor.authorJohnson, Andrew R
dc.contributor.authorSidebottom, Ashley M
dc.contributor.authorSedio, Brian E
dc.contributor.authorKlitgaard, Andreas
dc.contributor.authorLarson, Charles B
dc.contributor.authorBoya P, Cristopher A
dc.contributor.authorTorres-Mendoza, Daniel
dc.contributor.authorGonzalez, David J
dc.contributor.authorSilva, Denise B
dc.contributor.authorMarques, Lucas M
dc.contributor.authorDemarque, Daniel P
dc.contributor.authorPociute, Egle
dc.contributor.authorO'Neill, Ellis C
dc.contributor.authorBriand, Enora
dc.contributor.authorHelfrich, Eric J N
dc.contributor.authorGranatosky, Eve A
dc.contributor.authorGlukhov, Evgenia
dc.contributor.authorRyffel, Florian
dc.contributor.authorHouson, Hailey
dc.contributor.authorMohimani, Hosein
dc.contributor.authorKharbush, Jenan J
dc.contributor.authorZeng, Yi
dc.contributor.authorVorholt, Julia A
dc.contributor.authorKurita, Kenji L
dc.contributor.authorCharusanti, Pep
dc.contributor.authorMcPhail, Kerry L
dc.contributor.authorNielsen, Kristian Fog
dc.contributor.authorVuong, Lisa
dc.contributor.authorElfeki, Maryam
dc.contributor.authorTraxler, Matthew F
dc.contributor.authorEngene, Niclas
dc.contributor.authorKoyama, Nobuhiro
dc.contributor.authorVining, Oliver B
dc.contributor.authorBaric, Ralph
dc.contributor.authorSilva, Ricardo R
dc.contributor.authorMascuch, Samantha J
dc.contributor.authorTomasi, Sophie
dc.contributor.authorJenkins, Stefan
dc.contributor.authorMacherla, Venkat
dc.contributor.authorHoffman, Thomas
dc.contributor.authorAgarwal, Vinayak
dc.contributor.authorWilliams, Philip G
dc.contributor.authorDai, Jingqui
dc.contributor.authorNeupane, Ram
dc.contributor.authorGurr, Joshua
dc.contributor.authorRodríguez, Andrés M C
dc.contributor.authorLamsa, Anne
dc.contributor.authorZhang, Chen
dc.contributor.authorDorrestein, Kathleen
dc.contributor.authorDuggan, Brendan M
dc.contributor.authorAlmaliti, Jehad
dc.contributor.authorAllard, Pierre-Marie
dc.contributor.authorPhapale, Prasad
dc.contributor.authorNothias, Louis-Felix
dc.contributor.authorAlexandrov, Theodore
dc.contributor.authorLitaudon, Marc
dc.contributor.authorWolfender, Jean-Luc
dc.contributor.authorKyle, Jennifer E
dc.contributor.authorMetz, Thomas O
dc.contributor.authorPeryea, Tyler
dc.contributor.authorNguyen, Dac-Trung
dc.contributor.authorVanLeer, Danielle
dc.contributor.authorShinn, Paul
dc.contributor.authorJadhav, Ajit
dc.contributor.authorMüller, Rolf
dc.contributor.authorWaters, Katrina M
dc.contributor.authorShi, Wenyuan
dc.contributor.authorLiu, Xueting
dc.contributor.authorZhang, Lixin
dc.contributor.authorKnight, Rob
dc.contributor.authorJensen, Paul R
dc.contributor.authorPalsson, Bernhard Ø
dc.contributor.authorPogliano, Kit
dc.contributor.authorLinington, Roger G
dc.contributor.authorGutiérrez, Marcelino
dc.contributor.authorLopes, Norberto P
dc.contributor.authorGerwick, William H
dc.contributor.authorMoore, Bradley S
dc.contributor.authorDorrestein, Pieter C
dc.contributor.authorBandeira, Nuno
dc.date.accessioned2016-10-27T09:10:59Z
dc.date.available2016-10-27T09:10:59Z
dc.date.issued2016-08-09
dc.identifier.citationSharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. 2016, 34 (8):828-37 Nat. Biotechnol.en
dc.identifier.issn1546-1696
dc.identifier.pmid27504778
dc.identifier.doi10.1038/nbt.3597
dc.identifier.urihttp://hdl.handle.net/10033/620564
dc.description.abstractThe potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry (MS) techniques are well-suited to high-throughput characterization of NP, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social Molecular Networking (GNPS; http://gnps.ucsd.edu), an open-access knowledge base for community-wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of 'living data' through continuous reanalysis of deposited data.
dc.languageENG
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleSharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.
dc.typeArticleen
dc.contributor.departmentHelmholtz-Institute for Pharmaceutical Research Saarland (HIPS),Saarland Universitätscampus E8.1, 66123 Saarbrücken, Germany.en
dc.identifier.journalNature biotechnologyen
refterms.dateFOA2017-03-15T00:00:00Z
html.description.abstractThe potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry (MS) techniques are well-suited to high-throughput characterization of NP, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social Molecular Networking (GNPS; http://gnps.ucsd.edu), an open-access knowledge base for community-wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of 'living data' through continuous reanalysis of deposited data.


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