Browsing publications of the department of microbial drugs (MWIS) by Subject (MeSH)
Now showing items 1-1 of 1
Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe.(2007-07)Bioassay-guided isolation of antiviral compounds from the cultured cyanobacterium Microcystis ichthyoblabe provided two novel cyclic depsipeptides, ichthyopeptins A (1) and B (2). Their structures were determined by 1D (1H and 13C) and 2D (COSY, TOCSY, ROESY, HMQC, and HMBC) NMR spectra, ESIMS-MS, and amino acid analysis. The fraction containing both cyclic depsipeptides exhibited antiviral activity against influenza A virus with an IC50 value of 12.5 microg/mL.