Saccharide-Containing Dynamic Proteoids.
dc.contributor.author | Liu, Yun | |
dc.contributor.author | Stuart, Marc C A | |
dc.contributor.author | Witte, Martin D | |
dc.contributor.author | Buhler, Eric | |
dc.contributor.author | Hirsch, Anna K H | |
dc.date.accessioned | 2017-11-01T08:31:27Z | |
dc.date.available | 2017-11-01T08:31:27Z | |
dc.date.issued | 2017-10-05 | |
dc.identifier.citation | Saccharide-Containing Dynamic Proteoids. 2017 Chemistry | en |
dc.identifier.issn | 1521-3765 | |
dc.identifier.pmid | 28981987 | |
dc.identifier.doi | 10.1002/chem.201703584 | |
dc.identifier.uri | http://hdl.handle.net/10033/621147 | |
dc.description.abstract | Dynamic proteoids are dynamic covalent analogues of proteins, which can be used as new adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers. | |
dc.language.iso | en | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | * |
dc.title | Saccharide-Containing Dynamic Proteoids. | en |
dc.type | Article | en |
dc.contributor.department | Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Universitycampus E8.1, 66123 Saarbrücken, Germany. | en |
dc.identifier.journal | Chemistry (Weinheim an der Bergstrasse, Germany) | en |
refterms.dateFOA | 2018-06-13T00:01:46Z | |
html.description.abstract | Dynamic proteoids are dynamic covalent analogues of proteins, which can be used as new adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers. |