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dc.contributor.authorAkeus, Paulina
dc.contributor.authorSzeponik, Louis
dc.contributor.authorAhlmanner, Filip
dc.contributor.authorSundström, Patrik
dc.contributor.authorAlsén, Samuel
dc.contributor.authorGustavsson, Bengt
dc.contributor.authorSparwasser, Tim
dc.contributor.authorRaghavan, Sukanya
dc.contributor.authorQuiding-Järbrink, Marianne
dc.date.accessioned2018-06-18T08:17:07Z
dc.date.available2018-06-18T08:17:07Z
dc.date.issued2018-04-18
dc.identifier.issn1432-0851
dc.identifier.pmid29671006
dc.identifier.doi10.1007/s00262-018-2161-9
dc.identifier.urihttp://hdl.handle.net/10033/621400
dc.description.abstractTumor-infiltrating lymphocytes are crucial for anti-tumor immunity. We have previously shown that regulatory T cells (Treg) are able to reduce T-cell transendothelial migration in vitro and accumulation of effector T cells in intestinal tumors in vivo. Treg depletion also resulted in increased levels of the chemokines CXCL9 and CXCL10 specifically in the tumors. In this study, we investigated the mechanisms for Treg mediated suppression of T-cell migration into intestinal tumors in the APCen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectAPCmin/+en_US
dc.subjectCXCR3en_US
dc.subjectColon canceren_US
dc.subjectMigrationen_US
dc.subjectRegulatory T cellsen_US
dc.titleRegulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APC mice.en_US
dc.typeArticleen_US
dc.contributor.departmentTWINCORE, Zentrum für experimentelle uns klinische Ifektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.en_US
refterms.dateFOA2018-06-18T08:17:08Z
dc.source.journaltitleCancer immunology, immunotherapy : CII


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 3.0 United States