Show simple item record

dc.contributor.authorBrugiroux, Sandrine
dc.contributor.authorBeutler, Markus
dc.contributor.authorPfann, Carina
dc.contributor.authorGarzetti, Debora
dc.contributor.authorRuscheweyh, Hans-Joachim
dc.contributor.authorRing, Diana
dc.contributor.authorDiehl, Manuel
dc.contributor.authorHerp, Simone
dc.contributor.authorLötscher, Yvonne
dc.contributor.authorHussain, Saib
dc.contributor.authorBunk, Boyke
dc.contributor.authorPukall, Rüdiger
dc.contributor.authorHuson, Daniel H
dc.contributor.authorMünch, Philipp C
dc.contributor.authorMcHardy, Alice C
dc.contributor.authorMcCoy, Kathy D
dc.contributor.authorMacpherson, Andrew J
dc.contributor.authorLoy, Alexander
dc.contributor.authorClavel, Thomas
dc.contributor.authorBerry, David
dc.contributor.authorStecher, Bärbel
dc.date.accessioned2018-08-09T08:29:56Z
dc.date.available2018-08-09T08:29:56Z
dc.date.issued2016-11-21
dc.identifier.issn2058-5276
dc.identifier.pmid27869789
dc.identifier.doi10.1038/nmicrobiol.2016.215
dc.identifier.urihttp://hdl.handle.net/10033/621445
dc.description.abstractProtection against enteric infections, also termed colonization resistance, results from mutualistic interactions of the host and its indigenous microbes. The gut microbiota of humans and mice is highly diverse and it is therefore challenging to assign specific properties to its individual members. Here, we have used a collection of murine bacterial strains and a modular design approach to create a minimal bacterial community that, once established in germ-free mice, provided colonization resistance against the human enteric pathogen Salmonella enterica serovar Typhimurium (S. Tm). Initially, a community of 12 strains, termed Oligo-Mouse-Microbiota (Oligo-MMen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.titleGenome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium.en_US
dc.typeArticleen_US
dc.contributor.departmentBRICS, Braunschweiger Zentrum für Systembiologie, Rebenring 56, 38106 Braunschweig, Germany.en_US
refterms.dateFOA2018-08-09T08:29:56Z
dc.source.journaltitleNature microbiology


Files in this item

Thumbnail
Name:
Brugiroux et al.pdf
Size:
1.180Mb
Format:
PDF
Description:
original manuscript
Thumbnail
Name:
Brugiroux et al, Supplementary ...
Size:
1.830Mb
Format:
PDF
Description:
Supplementary figures 1-8 plus ...
Thumbnail
Name:
Supplementary Table 5.xlsx
Size:
24.46Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 5
Thumbnail
Name:
Supplementary Table 6.xlsx
Size:
15.70Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 6
Thumbnail
Name:
Supplementary Table 7.xlsx
Size:
39.71Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 7
Thumbnail
Name:
Supplementary Table 8.xlsx
Size:
30.67Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 8
Thumbnail
Name:
Supplementary Table 9.xlsx
Size:
60.57Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 9
Thumbnail
Name:
Supplementary Table 10.xlsx
Size:
33.42Kb
Format:
Microsoft Excel 2007
Description:
supplementary table 10

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-ShareAlike 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 3.0 United States