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dc.contributor.authorCheng, Tian
dc.contributor.authorChepkirui, Clara
dc.contributor.authorDecock, Cony
dc.contributor.authorMatasyoh, Josphat Clement
dc.contributor.authorStadler, Marc
dc.date.accessioned2019-06-21T14:34:18Z
dc.date.available2019-06-21T14:34:18Z
dc.date.issued2019-05-24
dc.identifier.citationJ Nat Prod. 2019 May 24;82(5):1283-1291. doi: 10.1021/acs.jnatprod.8b01086. Epub 2019 Apr 19.en_US
dc.identifier.issn1520-6025
dc.identifier.pmid31001977
dc.identifier.doi10.1021/acs.jnatprod.8b01086
dc.identifier.urihttp://hdl.handle.net/10033/621824
dc.description.abstractDuring the course of searching for new anti-infective and other biologically active secondary metabolites from Kenyan basidiomycetes, 13 previously undescribed metabolites, (6 R,7 S,10 R)-7,10-epoxy-7,11-dimethyldodec-1-ene-6,11-diol (1) and 12 sesquiterpenes named elgonenes A-L (2-13), and the known compound P-coumaric acid (14) were isolated from a basidiomycete collected in Mount Elgon Natural Reserve. The producing organism represents a new species of the genus Sanghuangporus, which is one of the segregates of the important traditional Asian medicinal mushrooms that were formerly known as the " Inonotus linteus" complex. The structure elucidation of compounds 1-13, based on 2D NMR spectroscopy, high-resolution mass spectrometry, and other spectral methods, and their antibacterial, antifungal, and cytotoxic activities are reported.en_US
dc.language.isoenen_US
dc.publisherAmerican Cemical Society (ACS)en_US
dc.relation.urlttps://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.8b01086en_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleSesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus.en_US
dc.typeArticleen_US
dc.contributor.departmentHZI,Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7,38124 Braunschweig, Germany.en_US
dc.identifier.journalJournal of Natural Productsen_US
dc.source.journaltitleJournal of natural products


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