2.50
Hdl Handle:
http://hdl.handle.net/10033/214238
Title:
Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.
Authors:
Bihrer, Verena; Friedrich-Rust, Mireen; Kronenberger, Bernd; Forestier, Nicole; Haupenthal, Jörg; Shi, Ying; Peveling-Oberhag, Jan; Radeke, Heinfried H; Sarrazin, Christoph; Herrmann, Eva; Zeuzem, Stefan; Waidmann, Oliver; Piiper, Albrecht
Abstract:
The liver contains large amounts of microRNA-122 (miR-122), whereas other tissues contain only marginal amounts of this miRNA. MicroRNAs have also been found to circulate in the blood in a cell-free form; their potential as readily accessible disease markers is currently evaluated. Here, we investigated if the serum levels of miR-122 might be useful as disease parameter in patients with chronic hepatitis C virus (HCV) infection.
Affiliation:
Department of Medicine I, University of Frankfurt/M., Frankfurt, Germany.
Citation:
Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection. 2011, 106 (9):1663-9 Am. J. Gastroenterol.
Journal:
The American journal of gastroenterology
Issue Date:
Sep-2011
URI:
http://hdl.handle.net/10033/214238
DOI:
10.1038/ajg.2011.161
PubMed ID:
21606975
Type:
Article
Language:
en
ISSN:
1572-0241
Appears in Collections:
publications of the department drug design and optimization (HIPS]DDOP)

Full metadata record

DC FieldValue Language
dc.contributor.authorBihrer, Verenaen
dc.contributor.authorFriedrich-Rust, Mireenen
dc.contributor.authorKronenberger, Bernden
dc.contributor.authorForestier, Nicoleen
dc.contributor.authorHaupenthal, Jörgen
dc.contributor.authorShi, Yingen
dc.contributor.authorPeveling-Oberhag, Janen
dc.contributor.authorRadeke, Heinfried Hen
dc.contributor.authorSarrazin, Christophen
dc.contributor.authorHerrmann, Evaen
dc.contributor.authorZeuzem, Stefanen
dc.contributor.authorWaidmann, Oliveren
dc.contributor.authorPiiper, Albrechten
dc.date.accessioned2012-03-05T14:52:18Z-
dc.date.available2012-03-05T14:52:18Z-
dc.date.issued2011-09-
dc.identifier.citationSerum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection. 2011, 106 (9):1663-9 Am. J. Gastroenterol.en
dc.identifier.issn1572-0241-
dc.identifier.pmid21606975-
dc.identifier.doi10.1038/ajg.2011.161-
dc.identifier.urihttp://hdl.handle.net/10033/214238-
dc.description.abstractThe liver contains large amounts of microRNA-122 (miR-122), whereas other tissues contain only marginal amounts of this miRNA. MicroRNAs have also been found to circulate in the blood in a cell-free form; their potential as readily accessible disease markers is currently evaluated. Here, we investigated if the serum levels of miR-122 might be useful as disease parameter in patients with chronic hepatitis C virus (HCV) infection.en
dc.language.isoenen
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshAlanine Transaminaseen
dc.subject.meshAspartate Aminotransferasesen
dc.subject.meshBilirubinen
dc.subject.meshBiological Markersen
dc.subject.meshFemaleen
dc.subject.meshHepatitis C, Chronicen
dc.subject.meshHumansen
dc.subject.meshInternational Normalized Ratioen
dc.subject.meshLiveren
dc.subject.meshMaleen
dc.subject.meshMicroRNAsen
dc.subject.meshMiddle Ageden
dc.subject.meshNecrosisen
dc.subject.meshSerum Albuminen
dc.titleSerum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.en
dc.typeArticleen
dc.contributor.departmentDepartment of Medicine I, University of Frankfurt/M., Frankfurt, Germany.en
dc.identifier.journalThe American journal of gastroenterologyen

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