2.50
Hdl Handle:
http://hdl.handle.net/10033/297473
Title:
Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis.
Authors:
Rohde, Manfred; Chhatwal, G Singh
Abstract:
Streptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections.
Affiliation:
Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany. manfred.rohde@helmholtz-hzi.de
Citation:
Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. 2013, 368:83-110 Curr. Top. Microbiol. Immunol.
Journal:
Current topics in microbiology and immunology
Issue Date:
2013
URI:
http://hdl.handle.net/10033/297473
DOI:
10.1007/82_2012_281
PubMed ID:
23203001
Type:
Book chapter
Language:
en
ISSN:
0070-217X
Appears in Collections:
Publications of Dept. Medizinische Mikrobiologie (MMIK)

Full metadata record

DC FieldValue Language
dc.contributor.authorRohde, Manfreden_GB
dc.contributor.authorChhatwal, G Singhen_GB
dc.date.accessioned2013-08-07T09:02:06Z-
dc.date.available2013-08-07T09:02:06Z-
dc.date.issued2013-
dc.identifier.citationAdherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. 2013, 368:83-110 Curr. Top. Microbiol. Immunol.en_GB
dc.identifier.issn0070-217X-
dc.identifier.pmid23203001-
dc.identifier.doi10.1007/82_2012_281-
dc.identifier.urihttp://hdl.handle.net/10033/297473-
dc.description.abstractStreptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Current topics in microbiology and immunologyen_GB
dc.subject.meshAdhesins, Bacterialen_GB
dc.subject.meshBacterial Adhesionen_GB
dc.subject.meshEpithelial Cellsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshStreptococcal Infectionsen_GB
dc.subject.meshStreptococcusen_GB
dc.titleAdherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis.en
dc.typeBook chapteren
dc.contributor.departmentDepartment of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany. manfred.rohde@helmholtz-hzi.deen_GB
dc.identifier.journalCurrent topics in microbiology and immunologyen_GB

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