Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011.

2.50
Hdl Handle:
http://hdl.handle.net/10033/302198
Title:
Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011.
Authors:
Balabanova, Yanina; Klar, Stefanie; Deleré, Yvonne; Wilking, Hendrik; Faber, Mirko S; Lassen, Sofie Gillesberg; Gilsdorf, Andreas; Dupke, Susann; Nitschke, Martin; Sayk, Friedhelm; Grunow, Roland; Krause, Gérard ( 0000-0003-3328-8808 )
Abstract:
The largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts.
Affiliation:
Robert Koch Institute, Berlin, Germany.
Citation:
Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011. 2013, 8 (9):e73052 PLoS ONE
Journal:
PloS one
Issue Date:
2013
URI:
http://hdl.handle.net/10033/302198
DOI:
10.1371/journal.pone.0073052
PubMed ID:
24039858
Type:
Article
Language:
en
ISSN:
1932-6203
Appears in Collections:
Publications of the department of epidemiology (EPID)

Full metadata record

DC FieldValue Language
dc.contributor.authorBalabanova, Yaninaen
dc.contributor.authorKlar, Stefanieen
dc.contributor.authorDeleré, Yvonneen
dc.contributor.authorWilking, Hendriken
dc.contributor.authorFaber, Mirko Sen
dc.contributor.authorLassen, Sofie Gillesbergen
dc.contributor.authorGilsdorf, Andreasen
dc.contributor.authorDupke, Susannen
dc.contributor.authorNitschke, Martinen
dc.contributor.authorSayk, Friedhelmen
dc.contributor.authorGrunow, Rolanden
dc.contributor.authorKrause, Gérarden
dc.date.accessioned2013-09-24T13:28:54Zen
dc.date.available2013-09-24T13:28:54Zen
dc.date.issued2013en
dc.identifier.citationSerological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011. 2013, 8 (9):e73052 PLoS ONEen
dc.identifier.issn1932-6203en
dc.identifier.pmid24039858en
dc.identifier.doi10.1371/journal.pone.0073052en
dc.identifier.urihttp://hdl.handle.net/10033/302198en
dc.description.abstractThe largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts.en
dc.language.isoenen
dc.rightsArchived with thanks to PloS oneen
dc.titleSerological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011.en
dc.typeArticleen
dc.contributor.departmentRobert Koch Institute, Berlin, Germany.en
dc.identifier.journalPloS oneen

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