Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae.

2.50
Hdl Handle:
http://hdl.handle.net/10033/593575
Title:
Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae.
Authors:
Rebets, Yuriy; Tokovenko, Bogdan; Lushchyk, Igor; Rückert, Christian; Zaburannyi, Nestor; Bechthold, Andreas; Kalinowski, Jörn; Luzhetskyy, Andriy ( 0000-0001-6497-0047 )
Abstract:
Kutzneria is a representative of a rarely observed genus of the family Pseudonocardiaceae. Kutzneria species were initially placed in the Streptosporangiaceae genus and later reconsidered to be an independent genus of the Pseudonocardiaceae. Kutzneria albida is one of the eight known members of the genus. This strain is a unique producer of the glycosylated polyole macrolide aculeximycin which is active against both bacteria and fungi. Kutzneria albida genome sequencing and analysis allow a deeper understanding of evolution of this genus of Pseudonocardiaceae, provide new insight in the phylogeny of the genus, as well as decipher the hidden secondary metabolic potential of these rare actinobacteria.
Affiliation:
Helmholtz Institute for Pharmaceutical Research Saarland (HIPS);Saarland University, Building A4.1, 66123 Saarbruecken, Germany.
Citation:
Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae. 2014, 15:885 BMC Genomics
Journal:
BMC genomics
Issue Date:
2014
URI:
http://hdl.handle.net/10033/593575
DOI:
10.1186/1471-2164-15-885
PubMed ID:
25301375
Type:
Article
Language:
en
ISSN:
1471-2164
Appears in Collections:
publications of the research group metabolic engineering of Actinomycetes ([HIPS]AMEG)

Full metadata record

DC FieldValue Language
dc.contributor.authorRebets, Yuriyen
dc.contributor.authorTokovenko, Bogdanen
dc.contributor.authorLushchyk, Igoren
dc.contributor.authorRückert, Christianen
dc.contributor.authorZaburannyi, Nestoren
dc.contributor.authorBechthold, Andreasen
dc.contributor.authorKalinowski, Jörnen
dc.contributor.authorLuzhetskyy, Andriyen
dc.date.accessioned2016-01-15T15:37:09Zen
dc.date.available2016-01-15T15:37:09Zen
dc.date.issued2014en
dc.identifier.citationComplete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae. 2014, 15:885 BMC Genomicsen
dc.identifier.issn1471-2164en
dc.identifier.pmid25301375en
dc.identifier.doi10.1186/1471-2164-15-885en
dc.identifier.urihttp://hdl.handle.net/10033/593575en
dc.description.abstractKutzneria is a representative of a rarely observed genus of the family Pseudonocardiaceae. Kutzneria species were initially placed in the Streptosporangiaceae genus and later reconsidered to be an independent genus of the Pseudonocardiaceae. Kutzneria albida is one of the eight known members of the genus. This strain is a unique producer of the glycosylated polyole macrolide aculeximycin which is active against both bacteria and fungi. Kutzneria albida genome sequencing and analysis allow a deeper understanding of evolution of this genus of Pseudonocardiaceae, provide new insight in the phylogeny of the genus, as well as decipher the hidden secondary metabolic potential of these rare actinobacteria.en
dc.language.isoenen
dc.subject.meshActinomycetalesen
dc.subject.meshAnti-Bacterial Agentsen
dc.subject.meshGenome, Bacterialen
dc.subject.meshGenomicsen
dc.subject.meshGlycopeptidesen
dc.subject.meshMacrolidesen
dc.subject.meshMultigene Familyen
dc.subject.meshPhylogenyen
dc.subject.meshSequence Homology, Nucleic Aciden
dc.titleComplete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Institute for Pharmaceutical Research Saarland (HIPS);Saarland University, Building A4.1, 66123 Saarbruecken, Germany.en
dc.identifier.journalBMC genomicsen

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