Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus.

2.50
Hdl Handle:
http://hdl.handle.net/10033/614916
Title:
Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus.
Authors:
Bokkasam, Harish; Ernst, Matthias; Guenther, Marco; Wagner, Christian; Schaefer, Ulrich F; Lehr, Claus-Michael
Abstract:
Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate-plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus.
Affiliation:
Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken.
Citation:
Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus. 2016: Int J Pharm
Journal:
International journal of pharmaceutics
Issue Date:
13-Jun-2016
URI:
http://hdl.handle.net/10033/614916
DOI:
10.1016/j.ijpharm.2016.06.035
PubMed ID:
27311353
Type:
Article
ISSN:
1873-3476
Appears in Collections:
publications of the department drug delivery ([TC] DDEL)

Full metadata record

DC FieldValue Language
dc.contributor.authorBokkasam, Harishen
dc.contributor.authorErnst, Matthiasen
dc.contributor.authorGuenther, Marcoen
dc.contributor.authorWagner, Christianen
dc.contributor.authorSchaefer, Ulrich Fen
dc.contributor.authorLehr, Claus-Michaelen
dc.date.accessioned2016-06-28T14:04:30Z-
dc.date.available2016-06-28T14:04:30Z-
dc.date.issued2016-06-13-
dc.identifier.citationDifferent macro- and micro-rheological properties of native porcine respiratory and intestinal mucus. 2016: Int J Pharmen
dc.identifier.issn1873-3476-
dc.identifier.pmid27311353-
dc.identifier.doi10.1016/j.ijpharm.2016.06.035-
dc.identifier.urihttp://hdl.handle.net/10033/614916-
dc.description.abstractAim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate-plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus.en
dc.languageENG-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleDifferent macro- and micro-rheological properties of native porcine respiratory and intestinal mucus.-
dc.typeArticleen
dc.contributor.departmentHelmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken.en
dc.identifier.journalInternational journal of pharmaceuticsen

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