2.50
Hdl Handle:
http://hdl.handle.net/10033/620557
Title:
Toward Whole-Transcriptome Editing with CRISPR-Cas9.
Authors:
Heckl, Dirk; Charpentier, Emmanuelle
Abstract:
Targeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.
Affiliation:
Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Citation:
Toward Whole-Transcriptome Editing with CRISPR-Cas9. 2015, 58 (4):560-2 Mol. Cell
Journal:
Molecular cell
Issue Date:
21-May-2015
URI:
http://hdl.handle.net/10033/620557
DOI:
10.1016/j.molcel.2015.05.016
PubMed ID:
26000839
Type:
Article
ISSN:
1097-4164
Appears in Collections:
publications of the department Regulation of infection

Full metadata record

DC FieldValue Language
dc.contributor.authorHeckl, Dirken
dc.contributor.authorCharpentier, Emmanuelleen
dc.date.accessioned2016-10-19T11:01:17Z-
dc.date.available2016-10-19T11:01:17Z-
dc.date.issued2015-05-21-
dc.identifier.citationToward Whole-Transcriptome Editing with CRISPR-Cas9. 2015, 58 (4):560-2 Mol. Cellen
dc.identifier.issn1097-4164-
dc.identifier.pmid26000839-
dc.identifier.doi10.1016/j.molcel.2015.05.016-
dc.identifier.urihttp://hdl.handle.net/10033/620557-
dc.description.abstractTargeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.en
dc.languageENG-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshCRISPR-Cas Systemsen
dc.subject.meshGene Expressionen
dc.subject.meshGenetic Engineeringen
dc.subject.meshGenetic Techniquesen
dc.subject.meshGenome, Humanen
dc.subject.meshHumansen
dc.subject.meshMelanomaen
dc.subject.meshTranscription, Geneticen
dc.subject.meshTranscriptional Activationen
dc.titleToward Whole-Transcriptome Editing with CRISPR-Cas9.
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalMolecular cellen

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