2.50
Hdl Handle:
http://hdl.handle.net/10033/620664
Title:
Acute and chronic infections with nonprimate hepacivirus in young horses.
Authors:
Gather, Theresa; Walter, Stephanie; Pfaender, Stephanie; Todt, Daniel; Feige, Karsten; Steinmann, Eike ( 0000-0002-8771-4262 ) ; Cavalleri, Jessika M V
Abstract:
The recently discovered nonprimate hepacivirus (NPHV) naturally infects horses and is the closest known homolog of hepatitis C virus to date. Within a follow-up study acute field infections were monitored in four young Thoroughbred horses until the ages of 12-13 months. Serum samples were analyzed for the presence of NPHV RNA and anti-NPHV NS3 antibodies and liver specific parameters were evaluated. The four young horses were not able to clear infection, but remained chronically infected for the entire monitored time period despite the presence of NPHV specific antibodies.
Affiliation:
Twincore Centre of Experimental and Clinical Infection Research; a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover 30625, Germany.
Citation:
Acute and chronic infections with nonprimate hepacivirus in young horses. 2016, 47 (1):97 Vet. Res.
Journal:
Veterinary research
Issue Date:
22-Sep-2016
URI:
http://hdl.handle.net/10033/620664
DOI:
10.1186/s13567-016-0381-6
PubMed ID:
27659317
Type:
Article
Language:
en
ISSN:
1297-9716
Appears in Collections:
publications of the research group virus transmission ([TC]VIRT)

Full metadata record

DC FieldValue Language
dc.contributor.authorGather, Theresaen
dc.contributor.authorWalter, Stephanieen
dc.contributor.authorPfaender, Stephanieen
dc.contributor.authorTodt, Danielen
dc.contributor.authorFeige, Karstenen
dc.contributor.authorSteinmann, Eikeen
dc.contributor.authorCavalleri, Jessika M Ven
dc.date.accessioned2016-12-14T09:20:28Z-
dc.date.available2016-12-14T09:20:28Z-
dc.date.issued2016-09-22-
dc.identifier.citationAcute and chronic infections with nonprimate hepacivirus in young horses. 2016, 47 (1):97 Vet. Res.en
dc.identifier.issn1297-9716-
dc.identifier.pmid27659317-
dc.identifier.doi10.1186/s13567-016-0381-6-
dc.identifier.urihttp://hdl.handle.net/10033/620664-
dc.description.abstractThe recently discovered nonprimate hepacivirus (NPHV) naturally infects horses and is the closest known homolog of hepatitis C virus to date. Within a follow-up study acute field infections were monitored in four young Thoroughbred horses until the ages of 12-13 months. Serum samples were analyzed for the presence of NPHV RNA and anti-NPHV NS3 antibodies and liver specific parameters were evaluated. The four young horses were not able to clear infection, but remained chronically infected for the entire monitored time period despite the presence of NPHV specific antibodies.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleAcute and chronic infections with nonprimate hepacivirus in young horses.en
dc.typeArticleen
dc.contributor.departmentTwincore Centre of Experimental and Clinical Infection Research; a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover 30625, Germany.en
dc.identifier.journalVeterinary researchen

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