2.50
Hdl Handle:
http://hdl.handle.net/10033/620787
Title:
QTLminer: identifying genes regulating quantitative traits
Authors:
Alberts, Rudi; Schughart, Klaus ( 0000-0002-6824-7523 )
Abstract:
Abstract Background Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to hundreds of genes. To find the most promising candidate genes that regulate the trait, the biologist typically collects information from multiple resources about the genes in the QTL interval. This process is very laborious and time consuming. Results QTLminer is a bioinformatics tool that automatically performs QTL region analysis. It is available in GeneNetwork and it integrates information such as gene annotation, gene expression and sequence polymorphisms for all the genes within a given genomic interval. Conclusions QTLminer substantially speeds up discovery of the most promising candidate genes within a QTL region.
Citation:
BMC Bioinformatics. 2010 Oct 15;11(1):516
Issue Date:
15-Oct-2010
URI:
http://dx.doi.org/10.1186/1471-2105-11-516; http://hdl.handle.net/10033/620787
Type:
Journal Article
Appears in Collections:
publications of the department infection genetics (INFG)

Full metadata record

DC FieldValue Language
dc.contributor.authorAlberts, Rudien
dc.contributor.authorSchughart, Klausen
dc.date.accessioned2017-01-27T11:47:43Z-
dc.date.available2017-01-27T11:47:43Z-
dc.date.issued2010-10-15en
dc.identifier.citationBMC Bioinformatics. 2010 Oct 15;11(1):516en
dc.identifier.urihttp://dx.doi.org/10.1186/1471-2105-11-516en
dc.identifier.urihttp://hdl.handle.net/10033/620787-
dc.description.abstractAbstract Background Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to hundreds of genes. To find the most promising candidate genes that regulate the trait, the biologist typically collects information from multiple resources about the genes in the QTL interval. This process is very laborious and time consuming. Results QTLminer is a bioinformatics tool that automatically performs QTL region analysis. It is available in GeneNetwork and it integrates information such as gene annotation, gene expression and sequence polymorphisms for all the genes within a given genomic interval. Conclusions QTLminer substantially speeds up discovery of the most promising candidate genes within a QTL region.en
dc.titleQTLminer: identifying genes regulating quantitative traitsen
dc.typeJournal Articleen
dc.language.rfc3066enen
dc.rights.holderAlberts and Schughart.en
dc.date.updated2015-09-04T08:26:10Zen
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