DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).
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Authors
Quentmeier, HilmarEberth, Sonja
Romani, Julia
Weich, Herbert A
Zaborski, Margarete
Drexler, Hans G
Issue Date
2012-01-17
Metadata
Show full item recordAbstract
Vascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by DNA methylation.Citation
DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). 2012, 12:19 BMC CancerAffiliation
Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.Journal
BMC cancerPubMed ID
22251800Type
ArticleLanguage
enISSN
1471-2407ae974a485f413a2113503eed53cd6c53
10.1186/1471-2407-12-19
Scopus Count
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- Creative Commons
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/