2.50
Hdl Handle:
http://hdl.handle.net/10033/620842
Title:
DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).
Authors:
Quentmeier, Hilmar; Eberth, Sonja; Romani, Julia; Weich, Herbert A; Zaborski, Margarete; Drexler, Hans G
Abstract:
Vascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by DNA methylation.
Affiliation:
Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Citation:
DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). 2012, 12:19 BMC Cancer
Journal:
BMC cancer
Issue Date:
17-Jan-2012
URI:
http://hdl.handle.net/10033/620842
DOI:
10.1186/1471-2407-12-19
PubMed ID:
22251800
Type:
Article
Language:
en
ISSN:
1471-2407
Appears in Collections:
Publications of Dept. Gene Regulation and Differentiation (RDIF)

Full metadata record

DC FieldValue Language
dc.contributor.authorQuentmeier, Hilmaren
dc.contributor.authorEberth, Sonjaen
dc.contributor.authorRomani, Juliaen
dc.contributor.authorWeich, Herbert Aen
dc.contributor.authorZaborski, Margareteen
dc.contributor.authorDrexler, Hans Gen
dc.date.accessioned2017-02-27T11:01:09Z-
dc.date.available2017-02-27T11:01:09Z-
dc.date.issued2012-01-17-
dc.identifier.citationDNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). 2012, 12:19 BMC Canceren
dc.identifier.issn1471-2407-
dc.identifier.pmid22251800-
dc.identifier.doi10.1186/1471-2407-12-19-
dc.identifier.urihttp://hdl.handle.net/10033/620842-
dc.description.abstractVascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by DNA methylation.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshBlotting, Westernen
dc.subject.meshCell Line, Tumoren
dc.subject.meshDNA Methylationen
dc.subject.meshEndothelial Cellsen
dc.subject.meshGene Expression Regulationen
dc.subject.meshHuman Umbilical Vein Endothelial Cellsen
dc.subject.meshHumansen
dc.subject.meshLeukemiaen
dc.subject.meshLymphomaen
dc.subject.meshReal-Time Polymerase Chain Reactionen
dc.subject.meshSequence Analysis, DNAen
dc.subject.meshVascular Endothelial Growth Factor Receptor-2en
dc.subject.meshVascular Endothelial Growth Factor Receptor-3en
dc.titleDNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalBMC canceren
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