2.50
Hdl Handle:
http://hdl.handle.net/10033/620845
Title:
Myxobacteria: natural pharmaceutical factories
Authors:
Diez, Juana; Martinez, Javier P; Mestres, Jordi; Sasse, Florenz; Frank, Ronald ( 0000-0003-2683-6511 ) ; Meyerhans, Andreas
Abstract:
Abstract Myxobacteria are amongst the top producers of natural products. The diversity and unique structural properties of their secondary metabolites is what make these social microbes highly attractive for drug discovery. Screening of products derived from these bacteria has revealed a puzzling amount of hits against infectious and non-infectious human diseases. Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution.
Affiliation:
Helmholtz Centre for infection research, Ihoffenstr. 7, 38124 Braunschweig, Germany.
Citation:
Microbial Cell Factories. 2012 Apr 30;11(1):52
Issue Date:
30-Apr-2012
URI:
http://dx.doi.org/10.1186/1475-2859-11-52; http://hdl.handle.net/10033/620845
Type:
Article
Appears in Collections:
Publications of the research group Chemical Biology (CBIO)

Full metadata record

DC FieldValue Language
dc.contributor.authorDiez, Juanaen
dc.contributor.authorMartinez, Javier Pen
dc.contributor.authorMestres, Jordien
dc.contributor.authorSasse, Florenzen
dc.contributor.authorFrank, Ronalden
dc.contributor.authorMeyerhans, Andreasen
dc.date.accessioned2017-03-06T11:42:08Z-
dc.date.available2017-03-06T11:42:08Z-
dc.date.issued2012-04-30-
dc.identifier.citationMicrobial Cell Factories. 2012 Apr 30;11(1):52en
dc.identifier.urihttp://dx.doi.org/10.1186/1475-2859-11-52-
dc.identifier.urihttp://hdl.handle.net/10033/620845-
dc.description.abstractAbstract Myxobacteria are amongst the top producers of natural products. The diversity and unique structural properties of their secondary metabolites is what make these social microbes highly attractive for drug discovery. Screening of products derived from these bacteria has revealed a puzzling amount of hits against infectious and non-infectious human diseases. Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution.en
dc.titleMyxobacteria: natural pharmaceutical factories-
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Ihoffenstr. 7, 38124 Braunschweig, Germany.en
dc.language.rfc3066enen
dc.rights.holderDiez et al.; licensee BioMed Central Ltd.en
dc.date.updated2015-09-04T08:25:28Zen
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