2.50
Hdl Handle:
http://hdl.handle.net/10033/620921
Title:
Blockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure.
Authors:
Khanam, Arshi; Trehanpati, Nirupma; Riese, Peggy ( 0000-0001-6796-6780 ) ; Rastogi, Archana; Guzman, Carlos A.; Sarin, Shiv Kumar
Abstract:
Neutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver injury in acute-on-chronic liver failure (ACLF) remains highly elusive; which could be targeted for the development of new therapeutic interventions.
Affiliation:
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Citation:
Blockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure. 2017, 8:464 Front Immunol
Journal:
Frontiers in immunology
Issue Date:
2017
URI:
http://hdl.handle.net/10033/620921
DOI:
10.3389/fimmu.2017.00464
PubMed ID:
28484461
Type:
Article
Language:
en
Appears in Collections:
publications of the research group vaccinology and applied microbiology (VAC)

Full metadata record

DC FieldValue Language
dc.contributor.authorKhanam, Arshien
dc.contributor.authorTrehanpati, Nirupmaen
dc.contributor.authorRiese, Peggyen
dc.contributor.authorRastogi, Archanaen
dc.contributor.authorGuzman, Carlos A.en
dc.contributor.authorSarin, Shiv Kumaren
dc.date.accessioned2017-05-17T12:07:22Z-
dc.date.available2017-05-17T12:07:22Z-
dc.date.issued2017-
dc.identifier.citationBlockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure. 2017, 8:464 Front Immunolen
dc.identifier.pmid28484461-
dc.identifier.doi10.3389/fimmu.2017.00464-
dc.identifier.urihttp://hdl.handle.net/10033/620921-
dc.description.abstractNeutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver injury in acute-on-chronic liver failure (ACLF) remains highly elusive; which could be targeted for the development of new therapeutic interventions.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleBlockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalFrontiers in immunologyen

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