In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633.

2.50
Hdl Handle:
http://hdl.handle.net/10033/620932
Title:
In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633.
Authors:
Ricci, Francesca; Murgia, Xabier; Razzetti, Roberta; Pelizzi, Nicola; Salomone, Fabrizio
Abstract:
CHF5633 is a new generation synthetic surfactant containing both SP-B and SP-C analogues developed for the treatment of respiratory distress syndrome. Here, the optimal dose and its performance in comparison to the animal-derived surfactant poractant alfa were investigated.
Affiliation:
Helmholtz Institut für pharmazeutische Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken, Germany.
Citation:
In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633. 2017, 81 (2):369-375 Pediatr. Res.
Journal:
Pediatric research
Issue Date:
Feb-2017
URI:
http://hdl.handle.net/10033/620932
DOI:
10.1038/pr.2016.231
PubMed ID:
27973472
Type:
Article
Language:
en
ISSN:
1530-0447
Appears in Collections:
publications of the department drug delivery ([TC] DDEL)

Full metadata record

DC FieldValue Language
dc.contributor.authorRicci, Francescaen
dc.contributor.authorMurgia, Xabieren
dc.contributor.authorRazzetti, Robertaen
dc.contributor.authorPelizzi, Nicolaen
dc.contributor.authorSalomone, Fabrizioen
dc.date.accessioned2017-06-01T09:23:41Z-
dc.date.available2017-06-01T09:23:41Z-
dc.date.issued2017-02-
dc.identifier.citationIn vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633. 2017, 81 (2):369-375 Pediatr. Res.en
dc.identifier.issn1530-0447-
dc.identifier.pmid27973472-
dc.identifier.doi10.1038/pr.2016.231-
dc.identifier.urihttp://hdl.handle.net/10033/620932-
dc.description.abstractCHF5633 is a new generation synthetic surfactant containing both SP-B and SP-C analogues developed for the treatment of respiratory distress syndrome. Here, the optimal dose and its performance in comparison to the animal-derived surfactant poractant alfa were investigated.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleIn vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Institut für pharmazeutische Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken, Germany.en
dc.identifier.journalPediatric researchen

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