Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

2.50
Hdl Handle:
http://hdl.handle.net/10033/620973
Title:
Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.
Authors:
Siddharta, Anindya; Pfaender, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco P; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker; Steinmann, Eike
Abstract:
The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.
Affiliation:
TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung gmbH, Feodor-Lynen Str. 7, 30625 Hannover, Germany.
Citation:
Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. 2017, 215 (6):902-906 J. Infect. Dis.
Journal:
The Journal of infectious diseases
Issue Date:
15-Mar-2017
URI:
http://hdl.handle.net/10033/620973
DOI:
10.1093/infdis/jix046
PubMed ID:
28453839
Type:
Article
Language:
en
ISSN:
1537-6613
Appears in Collections:
publications of the research group virus transmission ([TC]VIRT)

Full metadata record

DC FieldValue Language
dc.contributor.authorSiddharta, Anindyaen
dc.contributor.authorPfaender, Stephanieen
dc.contributor.authorVielle, Nathalie Janeen
dc.contributor.authorDijkman, Ronalden
dc.contributor.authorFriesland, Martinaen
dc.contributor.authorBecker, Brittaen
dc.contributor.authorYang, Jaewonen
dc.contributor.authorEngelmann, Michaelen
dc.contributor.authorTodt, Danielen
dc.contributor.authorWindisch, Marc Pen
dc.contributor.authorBrill, Florian Hen
dc.contributor.authorSteinmann, Joergen
dc.contributor.authorSteinmann, Jochenen
dc.contributor.authorBecker, Stephanen
dc.contributor.authorAlves, Marco Pen
dc.contributor.authorPietschmann, Thomasen
dc.contributor.authorEickmann, Markusen
dc.contributor.authorThiel, Volkeren
dc.contributor.authorSteinmann, Eikeen
dc.date.accessioned2017-06-22T09:40:09Z-
dc.date.available2017-06-22T09:40:09Z-
dc.date.issued2017-03-15-
dc.identifier.citationVirucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. 2017, 215 (6):902-906 J. Infect. Dis.en
dc.identifier.issn1537-6613-
dc.identifier.pmid28453839-
dc.identifier.doi10.1093/infdis/jix046-
dc.identifier.urihttp://hdl.handle.net/10033/620973-
dc.description.abstractThe World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleVirucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.en
dc.typeArticleen
dc.contributor.departmentTWINCORE, Zentrum für experimentelle und klinische Infektionsforschung gmbH, Feodor-Lynen Str. 7, 30625 Hannover, Germany.en
dc.identifier.journalThe Journal of infectious diseasesen

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