2.50
Hdl Handle:
http://hdl.handle.net/10033/621224
Title:
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.
Authors:
Pezoldt, Joern; Pisano, Fabio; Heine, Wiebke; Pasztoi, Maria; Rosenheinrich, Maik; Nuss, Aaron M; Pils, Marina C; Prinz, Immo; Förster, Reinhold; Huehn, Jochen; Dersch, Petra ( 0000-0001-8177-3280 )
Abstract:
To successfully limit pathogen dissemination, an immunological link between the entry tissue of the pathogen and the underlying secondary lymphoid organs (SLOs) needs to be established to prime adaptive immune responses. Here, the prerequisite of CCR7 to mount host immune responses within SLOs during gastrointestinal Yersinia pseudotuberculosis infection to limit pathogen spread was investigated.
Affiliation:
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr.7, 38124 Braunschweig, Germany.
Citation:
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection. 2017, 216 (6):752-760 J. Infect. Dis.
Journal:
The Journal of infectious diseases
Issue Date:
15-Sep-2017
URI:
http://hdl.handle.net/10033/621224
DOI:
10.1093/infdis/jix037
PubMed ID:
28329174
Type:
Article
Language:
en
ISSN:
1537-6613
Appears in Collections:
publications of the division experimentelle Immunologie (EXIM); publications of the department of molecular Infectionbiology (MIBI); publications of the service unit animal experimentation: (TEE)

Full metadata record

DC FieldValue Language
dc.contributor.authorPezoldt, Joernen
dc.contributor.authorPisano, Fabioen
dc.contributor.authorHeine, Wiebkeen
dc.contributor.authorPasztoi, Mariaen
dc.contributor.authorRosenheinrich, Maiken
dc.contributor.authorNuss, Aaron Men
dc.contributor.authorPils, Marina Cen
dc.contributor.authorPrinz, Immoen
dc.contributor.authorFörster, Reinholden
dc.contributor.authorHuehn, Jochenen
dc.contributor.authorDersch, Petraen
dc.date.accessioned2018-01-04T10:58:34Z-
dc.date.available2018-01-04T10:58:34Z-
dc.date.issued2017-09-15-
dc.identifier.citationImpact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection. 2017, 216 (6):752-760 J. Infect. Dis.en
dc.identifier.issn1537-6613-
dc.identifier.pmid28329174-
dc.identifier.doi10.1093/infdis/jix037-
dc.identifier.urihttp://hdl.handle.net/10033/621224-
dc.description.abstractTo successfully limit pathogen dissemination, an immunological link between the entry tissue of the pathogen and the underlying secondary lymphoid organs (SLOs) needs to be established to prime adaptive immune responses. Here, the prerequisite of CCR7 to mount host immune responses within SLOs during gastrointestinal Yersinia pseudotuberculosis infection to limit pathogen spread was investigated.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshAnimalsen
dc.subject.meshCell Movementen
dc.subject.meshDendritic Cellsen
dc.subject.meshGenetic Predisposition to Diseaseen
dc.subject.meshHost-Pathogen Interactionsen
dc.subject.meshIntestinesen
dc.subject.meshLymph Nodesen
dc.subject.meshMiceen
dc.subject.meshMyeloid Cellsen
dc.subject.meshPeyer's Patchesen
dc.subject.meshReceptors, CCR7en
dc.subject.meshTh17 Cellsen
dc.subject.meshYersinia pseudotuberculosisen
dc.subject.meshYersinia pseudotuberculosis Infectionsen
dc.titleImpact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr.7, 38124 Braunschweig, Germany.en
dc.identifier.journalThe Journal of infectious diseasesen

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