Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.

2.50
Hdl Handle:
http://hdl.handle.net/10033/621336
Title:
Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.
Authors:
Junge, Norman; Yuan, Qinggong; Vu, Thu Huong; Krooss, Simon; Bednarski, Christien; Balakrishnan, Asha; Cathomen, Toni; Manns, Michael P; Baumann, Ulrich; Sharma, Amar Deep; Ott, Michael
Abstract:
To stably correct tyrosinaemia in proliferating livers of fumarylacetoacetate-hydrolase knockout (Fah-/-)mice by homologous-recombination-mediated targeted addition of theFahgene.
Affiliation:
TWINCORE, Zentrum für experimentelle und klinischeInfektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.
Citation:
Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model. 2018, 10 (2):277-286 World J Hepatol
Journal:
World journal of hepatology
Issue Date:
27-Feb-2018
URI:
http://hdl.handle.net/10033/621336
DOI:
10.4254/wjh.v10.i2.277
PubMed ID:
29527263
Type:
Article
Language:
en
ISSN:
1948-5182
Appears in Collections:
publications of the TwinCore unit Infection immunology

Full metadata record

DC FieldValue Language
dc.contributor.authorJunge, Normanen
dc.contributor.authorYuan, Qinggongen
dc.contributor.authorVu, Thu Huongen
dc.contributor.authorKrooss, Simonen
dc.contributor.authorBednarski, Christienen
dc.contributor.authorBalakrishnan, Ashaen
dc.contributor.authorCathomen, Tonien
dc.contributor.authorManns, Michael Pen
dc.contributor.authorBaumann, Ulrichen
dc.contributor.authorSharma, Amar Deepen
dc.contributor.authorOtt, Michaelen
dc.date.accessioned2018-04-05T11:55:04Z-
dc.date.available2018-04-05T11:55:04Z-
dc.date.issued2018-02-27-
dc.identifier.citationHomologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model. 2018, 10 (2):277-286 World J Hepatolen
dc.identifier.issn1948-5182-
dc.identifier.pmid29527263-
dc.identifier.doi10.4254/wjh.v10.i2.277-
dc.identifier.urihttp://hdl.handle.net/10033/621336-
dc.description.abstractTo stably correct tyrosinaemia in proliferating livers of fumarylacetoacetate-hydrolase knockout (Fah-/-)mice by homologous-recombination-mediated targeted addition of theFahgene.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleHomologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.en
dc.typeArticleen
dc.contributor.departmentTWINCORE, Zentrum für experimentelle und klinischeInfektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.en
dc.identifier.journalWorld journal of hepatologyen

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